Your browser doesn't support javascript.
loading
Histo-blood group A is a risk factor for severe COVID-19.
Garibaldi, Pedro M M; Oliveira, Luciana C; da Fonseca, Benedito A; Auxiliadora-Martins, Maria; Miranda, Carlos H; Almado, Carlos E L; Langhi, Dante M; Gilio, Renato N; Palma, Leonardo C; Gomes, Bruno B M; Bottura, Camila; Barrientto, Larissa C; Donadel, Camila D; Calado, Rodrigo T; De Santis, Gil C.
Afiliação
  • Garibaldi PMM; Department of Medical Imaging, Haematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
  • Oliveira LC; Department of Medical Imaging, Haematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
  • da Fonseca BA; Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
  • Auxiliadora-Martins M; Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
  • Miranda CH; Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
  • Almado CEL; Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
  • Langhi DM; Department of Intensive Care Medicine, Serrana State Hospital, Serrana, Brazil.
  • Gilio RN; Department of Haematology and Hemotherapy, São Camilo Hospital, São Paulo, Brazil.
  • Palma LC; Department of Intensive Care Medicine, Américo Brasiliense State Hospital, Américo Brasiliense, Brazil.
  • Gomes BBM; Department of Medical Imaging, Haematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
  • Bottura C; Department of Intensive Care Medicine, Serrana State Hospital, Serrana, Brazil.
  • Barrientto LC; Department of Intensive Care Medicine, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
  • Donadel CD; Department of Intensive Care Medicine, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
  • Calado RT; Department of Medical Imaging, Haematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
  • De Santis GC; Department of Medical Imaging, Haematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, Brazil.
Transfus Med ; 32(3): 248-251, 2022 Jun.
Article em En | MEDLINE | ID: mdl-34085363
OBJECTIVES: Evaluate the impact of ABO histo-blood group type on COVID-19 severity. BACKGROUND: ABO histo-blood type has been associated with different outcomes in infectious diseases. It has also shown a higher proportion of type A patients with SARS-CoV-2. In this observational study, extracted from an ongoing clinical trial on the efficacy of convalescent plasma transfused in COVID-19 patients, we describe the impact of ABO blood type on the risk of developing severe COVID-19. MATERIALS AND METHODS: Seventy-two consecutive patients (37 type A, 23 type O, 11 type B, 1 type AB) with severe (respiratory failure) COVID-19 were included. Control group was composed of 160 individuals randomly selected from the same populational basis. RESULTS: Blood group A was overrepresented (51.39%) in the patient group in relation to the control group (30%), whereas blood group O was less represented (31.94%) in patient than in control group (48%). Odds ratio (A vs. O) was 2.581 (1.381-4.817), CI 95%; p = 0.004. Also, blood group A patients appeared to have more severe disease, given by the scores of the Sequential Organ Failure Assessment and Simplified Acute Physiologic Score 3 (p = 0.036 and p = 0.058, respectively). CONCLUSION: Histo-blood type A is associated with a higher risk of developing severe COVID-19 in relation to blood type O.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Transfus Med Assunto da revista: HEMATOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Transfus Med Assunto da revista: HEMATOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido