Carriage of two carbapenem-resistance genes in Pseudomonas aeruginosa isolated from hospital-acquired infections in children from Costa Rica: the importance of local epidemiology.
Antimicrob Resist Infect Control
; 10(1): 71, 2021 04 28.
Article
em En
| MEDLINE
| ID: mdl-33910633
BACKGROUND: The assessment of Hospital-acquired infections due to multidrug-resistant bacteria involves the use of a variety of commercial and laboratory-developed tests to detect antimicrobial resistance genes in bacterial pathogens; however, few are evaluated for use in low- and middle-income countries. METHODS: We used whole-genome sequencing, rapid commercial molecular tests, laboratory-developed tests and routine culture testing. RESULTS: We identified the carriage of the metallo-ß-lactamase blaVIM-2 and blaIMP-18 alleles in Carbapenem-Resistant Pseudomonas aeruginosa infections among children in Costa Rica. CONCLUSIONS: The blaIMP-18 allele is not present in the most frequently used commercial tests; thus, it is possible that the circulation of this resistance gene may be underdiagnosed in Costa Rica.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pseudomonas aeruginosa
/
Infecções por Pseudomonas
/
Infecção Hospitalar
Tipo de estudo:
Screening_studies
Limite:
Child
/
Humans
País/Região como assunto:
America central
/
Costa rica
Idioma:
En
Revista:
Antimicrob Resist Infect Control
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Costa Rica
País de publicação:
Reino Unido