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The methodological quality of 176,620 randomized controlled trials published between 1966 and 2018 reveals a positive trend but also an urgent need for improvement.
Vinkers, Christiaan H; Lamberink, Herm J; Tijdink, Joeri K; Heus, Pauline; Bouter, Lex; Glasziou, Paul; Moher, David; Damen, Johanna A; Hooft, Lotty; Otte, Willem M.
Afiliação
  • Vinkers CH; Department of Psychiatry and Department of Anatomy and Neurosciences, Amsterdam UMC, Amsterdam, the Netherlands.
  • Lamberink HJ; Department of Child Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, and Utrecht University, Utrecht, the Netherlands.
  • Tijdink JK; Department of Ethics, Law and Humanities, Amsterdam UMC, and Department of Philosophy, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Heus P; Cochrane Netherlands, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Bouter L; Department of Epidemiology and Data Science, Amsterdam UMC, and Department of Philosophy, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Glasziou P; Institute for Evidence-Based Healthcare, Bond University, Gold Coast, Australia.
  • Moher D; Centre for Journalology, Clinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, Canada.
  • Damen JA; Cochrane Netherlands, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Hooft L; Cochrane Netherlands, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Otte WM; Department of Child Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, and Utrecht University, Utrecht, the Netherlands.
PLoS Biol ; 19(4): e3001162, 2021 04.
Article em En | MEDLINE | ID: mdl-33872298

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Publicações / Ensaios Clínicos Controlados Aleatórios como Assunto Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: PLoS Biol Assunto da revista: BIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Publicações / Ensaios Clínicos Controlados Aleatórios como Assunto Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: PLoS Biol Assunto da revista: BIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda País de publicação: Estados Unidos