Your browser doesn't support javascript.
loading
Fischer Carbene Complexes: A Glance at Two Decades of Research on Higher-Order Cycloaddition Reactions.
Feliciano, Alberto; Vázquez, Juan L; Benítez-Puebla, Luis J; Velazco-Cabral, Iván; Cruz Cruz, David; Delgado, Francisco; Vázquez, Miguel A.
Afiliação
  • Feliciano A; Departamento de Química, Universidad de Guanajuato, Noria Alta S/N, 36050, Guanajuato, Gto, Mexico.
  • Vázquez JL; Departamento de Química, Universidad de Guanajuato, Noria Alta S/N, 36050, Guanajuato, Gto, Mexico.
  • Benítez-Puebla LJ; Departamento de Química, Universidad de Guanajuato, Noria Alta S/N, 36050, Guanajuato, Gto, Mexico.
  • Velazco-Cabral I; Departamento de Química, Universidad de Guanajuato, Noria Alta S/N, 36050, Guanajuato, Gto, Mexico.
  • Cruz Cruz D; Departamento de Química, Universidad de Guanajuato, Noria Alta S/N, 36050, Guanajuato, Gto, Mexico.
  • Delgado F; Departamento de Química Orgánica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Prol. Carpio y Plan de Ayala S/N, 11340, Cd. de Mexico, Mexico.
  • Vázquez MA; Departamento de Química, Universidad de Guanajuato, Noria Alta S/N, 36050, Guanajuato, Gto, Mexico.
Chemistry ; 27(32): 8233-8251, 2021 Jun 04.
Article em En | MEDLINE | ID: mdl-33871119
The structure of Fischer carbene complexes (FCCs) is electron deficient. If bearing an α,ß-unsaturated system, it can generate a wide variety of compounds by undergoing many different transformations, including higher-order cycloadditions. The latter are described as pericyclic reactions in which more than six electrons participate. These reactions have been employed in various areas of organic synthesis, resulting in highly selective compounds with a broad range of scaffolds. The first studies on higher-order cycloadditions involving FCCs frequently yielded competing byproducts. Many groups have attempted to increase selectivity by exploring distinct reaction conditions, reagents and co-catalysts (e. g., metal-mediated cycloadditions). The present review is the first to focus exclusively on using higher-order cycloadditions involving FCCs to synthesize carbocycles and heterocycles. Based on two decades of reports, an analysis is made of the main aspects of the mechanisms proposed for higher-order cycloadditions and the structural diversity obtained by the substituent effect.
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: México País de publicação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: México País de publicação: Alemanha