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Abdominal Surgery in Crohn's Disease: Risk Factors for Complications.
Sakurai Kimura, Cintia Mayumi; Scanavini Neto, Arceu; Queiroz, Natalia Sousa Freitas; Horvat, Natally; Camargo, Mariane Gouvea Monteiro; Borba, Marcelo Rodrigues; Sobrado, Carlos Walter; Cecconello, Ivan; Nahas, Sergio Carlos.
Afiliação
  • Sakurai Kimura CM; Department of Colon and Rectal Surgery, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
  • Scanavini Neto A; Department of Colon and Rectal Surgery, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
  • Queiroz NSF; Department of Gastroenterology, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
  • Horvat N; Department of Radiology, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
  • Camargo MGM; Department of Colon and Rectal Surgery, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
  • Borba MR; Department of Colon and Rectal Surgery, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
  • Sobrado CW; Department of Colon and Rectal Surgery, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
  • Cecconello I; Department of Colon and Rectal Surgery, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
  • Nahas SC; Department of Colon and Rectal Surgery, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
Inflamm Intest Dis ; 6(1): 18-24, 2021 Feb.
Article em En | MEDLINE | ID: mdl-33850835
INTRODUCTION: Abdominal surgery in patients with Crohn's disease (CD) is challenging, especially in the biologic era. The aim of this study was to evaluate factors associated with increased risk for postoperative complications in CD. METHODS: A retrospective study was conducted with consecutive patients who underwent abdominal surgery for CD from January 2012 to January 2018. RESULTS: Of 103 patients, 32% had postoperative complications. Gender, age, disease location and phenotype, hemoglobin and albumin levels, previous abdominal surgery, and preoperative optimization did not differ between the groups with or without complications. Thirty-five percent of the patients were under anti-TNF therapy, and this medication was not associated with increased risk for postoperative complications. Time since the onset of the disease was significantly higher in patients with complications (12.9 vs. 9.4, p = 0.04). In multivariate analysis, creation of ostomy and urgent surgery were the only variables independently associated with increased risk for complications (OR 3.2, 95% CI 1.12-9.46 and OR 2.94, 95% CI 0.98-9.09, respectively). CONCLUSION: Urgent surgery for CD should preferably be performed in specialized centers, and creation of stoma is not necessarily associated with lower rate of postoperative complications but rather less severe complications.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Inflamm Intest Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Inflamm Intest Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça