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The Short- and Long-Term Burden of Acute Pancreatitis in the United States: A Retrospective Cohort Study.
Pokras, Shibani; Ray, Markqayne; Zheng, Shan; Ding, Yao; Chen, Chi-Chang.
Afiliação
  • Pokras S; From the Value Evidence & Outcomes, GSK, Collegeville, PA.
  • Ray M; Health Outcomes, Policy, and Economics Program (HOPE), Rutgers University, New Brunswick, NJ.
  • Zheng S; From the Value Evidence & Outcomes, GSK, Collegeville, PA.
  • Ding Y; Real World Evidence, IQVIA, Plymouth Meeting, PA.
  • Chen CC; Real World Evidence, IQVIA, Plymouth Meeting, PA.
Pancreas ; 50(3): 330-340, 2021 03 01.
Article em En | MEDLINE | ID: mdl-33835963
OBJECTIVES: This retrospective cohort study assessed short- and long-term economic, clinical burden, and productivity impacts of acute pancreatitis (AP) in the United States. METHODS: United States claims data from patients hospitalized for AP (January 1, 2011-September-30, 2016) were sourced from MarketScan databases. Patients were categorized by index AP severity: severe intensive care unit (ICU), severe non-ICU, and other hospitalized patients. RESULTS: During index, 41,946 patients were hospitalized or visited an emergency department for AP. For inpatients, median (interquartile range) AP-related total cost was $13,187 ($12,822) and increased with AP severity (P < 0.0001). During the postindex year, median AP-related costs were higher (P < 0.0001) for severe ICU versus severe non-ICU and other hospitalized patients. Hours lost and costs due to absence and short-term disability were similar between categories. Long-term disability costs were higher (P = 0.005) for severe ICU versus other hospitalized patients. Factors associated with higher total all-cause costs in the year after discharge included AP severity, length of hospitalization, readmission, AP reoccurrence, progression to chronic pancreatitis, or new-onset diabetes (P < 0.0001). CONCLUSIONS: An AP event exerts substantial burden during hospitalization and involves long-term clinical and economic consequences, including loss of productivity, which increase with index AP event severity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pancreatite / Efeitos Psicossociais da Doença / Serviço Hospitalar de Emergência / Hospitalização / Unidades de Terapia Intensiva / Tempo de Internação Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Limite: Humans País/Região como assunto: America do norte Idioma: En Revista: Pancreas Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pancreatite / Efeitos Psicossociais da Doença / Serviço Hospitalar de Emergência / Hospitalização / Unidades de Terapia Intensiva / Tempo de Internação Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Limite: Humans País/Região como assunto: America do norte Idioma: En Revista: Pancreas Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos