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Neurological manifestations temporally associated with SARS-CoV-2 infection in pediatric patients in Mexico.
Sánchez-Morales, Areli Estela; Urrutia-Osorio, Marta; Camacho-Mendoza, Esteban; Rosales-Pedraza, Gustavo; Dávila-Maldonado, Luis; González-Duarte, Alejandra; Herrera-Mora, Patricia; Ruiz-García, Matilde.
Afiliação
  • Sánchez-Morales AE; Pediatric Neurology Department, National Institute of Pediatrics, Insurgentes Sur 3700-C, Mexico City, Mexico.
  • Urrutia-Osorio M; Pediatric Neurology Department, National Institute of Pediatrics, Insurgentes Sur 3700-C, Mexico City, Mexico.
  • Camacho-Mendoza E; Pediatric Neurology Department, National Institute of Pediatrics, Insurgentes Sur 3700-C, Mexico City, Mexico.
  • Rosales-Pedraza G; Infectious Diseases Department, National Institute of Health Sciences and Nutrition "Salvador Zubirán", Mexico City, Mexico.
  • Dávila-Maldonado L; Health Education Department, National Institute of Health Sciences and Nutrition "Salvador Zubirán", Mexico City, Mexico.
  • González-Duarte A; Neurology Department, National Institute of Health Sciences and Nutrition "Salvador Zubirán", Mexico City, Mexico.
  • Herrera-Mora P; Pediatric Neurology Department, National Institute of Pediatrics, Insurgentes Sur 3700-C, Mexico City, Mexico.
  • Ruiz-García M; Pediatric Neurology Department, National Institute of Pediatrics, Insurgentes Sur 3700-C, Mexico City, Mexico. matilde.ruizg@gmail.com.
Childs Nerv Syst ; 37(7): 2305-2312, 2021 07.
Article em En | MEDLINE | ID: mdl-33751228
PURPOSE: To describe the temporal association of specific acute neurological symptoms in pediatric patients with confirmed SARS-CoV-2 infection between May and August 2020. METHODS: We performed a recollection of all the clinical and laboratory data of patients having acute neurological symptoms temporally associated with SARS-CoV-2 infection at a third-level referral hospital in Mexico City (Instituto Nacional de Pediatría). Patients in an age group of 0-17 years with acute neurological signs (including ascending weakness with areflexia, diminished visual acuity, encephalopathy, ataxia, stroke, or weakness with plasma creatinine kinase (CK) elevation) were evaluated. RESULTS: Out of 23 patients with neurological manifestations, 10 (43%) had a confirmed SARS-CoV-2 infection. Among the infected patients, 5 (50%) were males aged 2-16 years old (median age 11.8 years old). Four (40%) patients confirmed a close contact with a relative positive for SARS-CoV-2, while 6 (60%) cases had a history of SARS-CoV-2-related symptoms over the previous 2 weeks. The following diagnoses were established: 3 cases of GBS, 2 of ON, 2 of AIS, one of myositis with rhabdomyolysis, one ACA, and one of anti-NMDA-R encephalitis. CONCLUSIONS: Neurological manifestations temporally associated with SARS-CoV-2 infection were noticed in the pediatric population even without respiratory symptoms. In this study, 2 of 6 symptomatic patients had mild respiratory symptoms and 4 had unspecific symptoms. During this pandemic, SARS-CoV-2 infection should be considered as etiology in patients with acute neurological symptoms, with or without previous respiratory manifestations, particularly in teenagers.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acidente Vascular Cerebral / COVID-19 Tipo de estudo: Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant / Male / Newborn País/Região como assunto: Mexico Idioma: En Revista: Childs Nerv Syst Assunto da revista: NEUROLOGIA / PEDIATRIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: México País de publicação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acidente Vascular Cerebral / COVID-19 Tipo de estudo: Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant / Male / Newborn País/Região como assunto: Mexico Idioma: En Revista: Childs Nerv Syst Assunto da revista: NEUROLOGIA / PEDIATRIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: México País de publicação: Alemanha