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Technological Maturity and Systematic Review of Medicinal Plants with Pharmacological Activity in the Central Nervous System.
Bastos, Eduardo M S; da Silva, Victor D A; Costa, Silvia L; Hanna, Samira A.
Afiliação
  • Bastos EMS; Postgraduate Program in Intellectual Property and Technology Transfer for Innovation, PROFNIT, Institute of Chemistry, Federal University of Bahia, Campus de Ondina, 40170-290 Salvador, Bahia, Brazil.
  • da Silva VDA; Bio-function Department, Neurochemistry and Cell Biology Laboratory, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, Brazil.
  • Costa SL; Bio-function Department, Neurochemistry and Cell Biology Laboratory, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, Brazil.
  • Hanna SA; Biointeraction Sciences Department, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, Brazil.
Recent Pat Biotechnol ; 15(2): 89-101, 2021 Oct 04.
Article em En | MEDLINE | ID: mdl-33726659
BACKGROUND: Medicinal plants present activities against neurodegenerative diseases with potential for the pharmaceutical industries. Therefore, the objective of this study was to investigate the current panorama of patents and articles of Brazilian medicinal plants with pharmacological activities in the Central Nervous System (CNS), regarding such aspects as the number of patents by countries, areas of knowledge, and technological maturity. METHODS: We carry out a technological exploration on the Questel Orbit® platform with the descriptors: Agave sisalana P., Amburana cearenses A., Dimorphandra mollis B., Jatropha curcas L., Poincianella pyramidalis T. and Prosopis juliflora (Sw.) DC. with pharmacological activity and scientific exploration in PubMed and Science Direct associated with the CNS in the title, abstract, and methodology. RESULTS: A total of 642 patents were identified between the years 1999-2019. India, China, and Brazil are highlighted, 6th place, out of a total of 48 countries. Of these, 30 patents were not in the National Institute of Industrial Property, and 10% are Brazilian in biotechnology and pharmaceutical products. Eleven articles were used in PubMed and Science Direct with scientific domains (anticancer, neuroprotection and anti-inflammatory). The Federal University of Bahia is highlighted, showing Technology Readiness Levels (TRL4), basic skills of pre-clinical research. CONCLUSION: Brazilian public universities have a significant role in the scientific, technological and innovative development of therapeutic assets for CNS.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plantas Medicinais Tipo de estudo: Systematic_reviews Idioma: En Revista: Recent Pat Biotechnol Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Emirados Árabes Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plantas Medicinais Tipo de estudo: Systematic_reviews Idioma: En Revista: Recent Pat Biotechnol Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Emirados Árabes Unidos