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The usefulness of intraoperative consultation for the diagnosis of borderline ovarian tumors.
Salcedo-Hernández, Rosa A; Cantú-de-León, David F; Pérez-Montiel, Delia; García-Pérez, Leticia; Lino-Silva, Leonardo S; Zepeda-Najar, César; Barquet-Muñoz, Salim A.
Afiliação
  • Salcedo-Hernández RA; Surgical Oncology, National Cancer Institute, Mexico City, Mexico.
  • Cantú-de-León DF; Gynecologic Oncology, National Cancer Institute, Mexico City, Mexico.
  • Pérez-Montiel D; Surgical pathology, National Cancer Institute, Mexico City, Mexico.
  • García-Pérez L; Surgical Oncology, National Cancer Institute, Mexico City, Mexico.
  • Lino-Silva LS; Surgical pathology, National Cancer Institute, Mexico City, Mexico.
  • Zepeda-Najar C; Surgical oncology, Hospital ángeles Tijuana, Tijuana, Baja California Norte, Mexico.
  • Barquet-Muñoz SA; Surgical Oncology, National Cancer Institute, Mexico City, Mexico.
Ann Transl Med ; 9(3): 261, 2021 Feb.
Article em En | MEDLINE | ID: mdl-33708888
BACKGROUND: Borderline ovarian tumors (BTs) must be recognized during the surgery by intraoperative consultation (IOC) to guide surgical treatment; however, this diagnosis can be imprecise. Therefore, this study aimed to evaluate the diagnostic accuracy of IOC for the diagnosis of BT. METHODS: A retrospective cohort study was carried out including all women diagnosed with a pelvic tumor consecutively surgically treated from 2005 to 2015 with IOC. We calculated the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and likelihood ratios (LR) for the IOC and BTs. RESULTS: A total of 758 patients were enrolled, the median age was 44 years, the median tumor size was 11.8 cm, and the median CA-125 levels were 45.65 U/µL. After IOC, 458 (64.1%) cases were diagnosed as benign, 111 (14.7%) as BT, and 161 (21.2%) as malignant. The definitive diagnosis was a benign tumor in 448 (59.1%) cases, BT in 110 (14.5%), and 200 (26.4%) cases were malignant. The diagnostic accuracy of the IOC for BT diagnosis was 89.8% (sensitivity =65.5%, specificity =93.9%). The diagnosis performance of IOC for the diagnosis between BT and benign tumors (n=546) had a sensitivity of 69.9%, a specificity of 98.4%, and a diagnostic accuracy of 84%; meanwhile for the diagnosis between BT and malignant tumors (n=242) IOC had a sensitivity of 92.3%, a specificity of 81.7%, and a diagnostic accuracy of 87%. CONCLUSIONS: For practitioners, knowing the accuracy and limitations of the IOC for BT enables the better selection of cases to perform a complete staging surgery.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Ann Transl Med Ano de publicação: 2021 Tipo de documento: Article País de afiliação: México País de publicação: China
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Ann Transl Med Ano de publicação: 2021 Tipo de documento: Article País de afiliação: México País de publicação: China