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Intravenous Regional Limb Perfusion in Standing and Recumbent Horses: A Comparative Radiographic Study.
Garcia, Adriana F S; Dória, Renata G S; Arantes, Julia A; Reginato, Gustavo M; Neubauer, Fernanda G; Ribeiro, Gesiane.
Afiliação
  • Garcia AFS; United Metropolitan Colleges (FMU), São Paulo, São Paulo, Brazil.
  • Dória RGS; Faculty of Animal Science and Food Engineering, Department of Veterinary Medicine, University of São Paulo (USP), Pirassununga, São Paulo, Brazil.
  • Arantes JA; Faculty of Animal Science and Food Engineering, Department of Veterinary Medicine, University of São Paulo (USP), Pirassununga, São Paulo, Brazil.
  • Reginato GM; Faculty of Animal Science and Food Engineering, Department of Veterinary Medicine, University of São Paulo (USP), Pirassununga, São Paulo, Brazil.
  • Neubauer FG; GNVETS, São Paulo, São Paulo, Brazil.
  • Ribeiro G; United Metropolitan Colleges (FMU), São Paulo, São Paulo, Brazil. Electronic address: gesiane.ferraz@fmu.br.
J Equine Vet Sci ; 98: 103373, 2021 03.
Article em En | MEDLINE | ID: mdl-33663721
Although pharmacokinetic studies of drugs administered by intravenous regional limb perfusion (IRLP) to treat equine orthopedic infections suggest efficient drug distribution in the limbs, it remains unclear whether drug perfusion is affected by the position of the horse during the procedure. This study compared the perfusion of a radiopaque contrast into tissues of the extremities of horses maintained in standing and recumbent positions during an IRLP. Radiopaque contrast was administered through IRLP into the cephalic vein of 10 healthy adult horses under general anesthesia and right lateral recumbency (RG) or under sedation and standing (SG). The same animals were used in both groups, respecting a two-week washout period. Sequential radiographic images were performed immediately at the beginning of contrast administration (T0) and after 10, 20, 30, 40, and 50 minutes. Tourniquets were removed after 30 minutes. The time required for the contrast to reach the hooves was compared between groups. Contrast reached the hooves faster in SG (114 ± 15 seconds) compared with RG (236 ± 29 seconds) (P < 0.5). SG showed more uniform perfusion of the limb vessels, whereas RG showed more deposition of the contrast in the lateral digital vein, with smaller amounts reaching the hooves. From T10 onward, soft tissue radiopacity increased, albeit more markedly in standing than in recumbent animals, remaining until T50. Contrast radiography evidenced that IRLP performed in standing position leads to a quicker and more uniform perfusion of the vasculature and a more noticeable diffusion to the tissues than in recumbent horses.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Posição Ortostática / Casco e Garras Limite: Animals Idioma: En Revista: J Equine Vet Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Posição Ortostática / Casco e Garras Limite: Animals Idioma: En Revista: J Equine Vet Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos