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Aromatic compounds from the endophytic fungus Asordaria conoidea and their allelochemical property using OSMAC strategy.
Arruda, Gabriel Leda de; Moraes, Gleys Kellen Aquino de; Junior, Aloísio Freitas Chagas; Araujo, Angela Regina; Chapla, Vanessa Mara.
Afiliação
  • Arruda GL; Graduate Program in Chemistry, Federal University of Tocantins, UFT, Gurupi, Brazil.
  • Moraes GKA; Graduate Program in Biotechnology, Federal University of Tocantins, UFT, Gurupi, Brazil.
  • Junior AFC; Graduate Program in Biotechnology, Federal University of Tocantins, UFT, Gurupi, Brazil.
  • Araujo AR; Organic Chemistry Department, São Paulo State University, UNESP, Chemistry Institute, Araraquara, Brazil.
  • Chapla VM; Graduate Program in Chemistry, Federal University of Tocantins, UFT, Gurupi, Brazil.
Nat Prod Res ; 36(15): 3999-4002, 2022 Aug.
Article em En | MEDLINE | ID: mdl-33663291
Endophytic fungi are biodiverse and alternative source of bioactive compounds, due their different abilities of genetic expression and alteration of biosynthetic pathway when submitted to different culture conditions. The metabolic profile of three different crude extracts (A, B and C), obtained from the endophytic fungus Asordaria conoidea, were evaluated by HPLC and 1H NMR. Antioxidant and allelochemical activity were also evaluated. OSMAC diversified the metabolic production, mainly in the solid culture, where the tyrosol, 4-hydroxybenzaldehyde, 2-phenylacetamide and vanillic acid were isolated. The structures of the compounds were elucidated mainly by NMR. Extracts had antioxidant potential, however, only Extract C showed allelochemical activity, as inhibition of 65.5% in growth. This study confirms the efficiency of the OSMAC platform in producing extracts of different properties and compounds. Herein the A. conoidea was isolated for the first time as an endophytic microorganism.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Feromônios / Sordariales Idioma: En Revista: Nat Prod Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Feromônios / Sordariales Idioma: En Revista: Nat Prod Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido