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Hyperbaric oxygen therapy decreases mortality due to Fournier's gangrene: a retrospective comparative study.
Feres, Omar; Feitosa, Marley Ribeiro; Ribeiro da Rocha, José Joaquim; Miranda, Juliana Mamede; Dos Santos, Luciana Egydio; Féres, Artur Cury; de Camargo, Hugo Parra; Parra, Rogério Serafim.
Afiliação
  • Feres O; Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
  • Feitosa MR; Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
  • Ribeiro da Rocha JJ; Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
  • Miranda JM; Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
  • Dos Santos LE; Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
  • Féres AC; Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
  • de Camargo HP; Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
  • Parra RS; Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Med Gas Res ; 11(1): 18-23, 2021.
Article em En | MEDLINE | ID: mdl-33642333
There is no consensus about the role of adjunctive hyperbaric oxygen therapy (HBOT) in the management of Fournier's gangrene. The aim of this study was to compare the evolution of patients with Fournier's gangrene treated with all classical measures with and without adjuvant HBOT. A retrospective comparative study regarding the evolution of patients treated for Fournier's gangrene was conducted in two periods. In period I, from 1990 to 2002, patients received standard treatments for Fournier's gangrene, which consisted of surgical debridement, antibiotic therapy and intensive care. In period II, from 2012 to 2019, adjunctive HBOT was added to the classical management strategy. All patients were assigned into four groups according to the anatomical severity classification and the area affected after the first debridement. This classification ensured that the groups could be comparable. The total number of patients in this study was 197, and these patients were divided into control group (118/59.9%) and HBOT group (79/40.1%). The mean age, comorbidities, and anatomical severity classification were similar between the two groups. In period I, 34 out of 118 (28.8%) patients died, while in the HBOT group, 3 out of 77 (3.7%) patients died (P < 0.001). The use of adjuvant HBOT in combination with classical treatment was associated with reduced mortality. This study was approved by the Institutional Review Board and the Ethics Committee of Ribeirão Preto Medical School, University of São Paulo, Brazil (No. 08/2018) on May 2, 2018.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Gangrena de Fournier / Oxigenoterapia Hiperbárica Tipo de estudo: Observational_studies Aspecto: Ethics Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Med Gas Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Austrália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Gangrena de Fournier / Oxigenoterapia Hiperbárica Tipo de estudo: Observational_studies Aspecto: Ethics Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Med Gas Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Austrália