Your browser doesn't support javascript.
loading
Computational and experimental analysis of a Glaucoma flat drainage device.
Panduro, R M R; Monterrey, Christian; Mantari, J L; Canahuire, Ruth; Alvarez, Helard; Miranda, Mario; Elsheikh, Ahmed.
Afiliação
  • Panduro RMR; Department of Mechanical Engineering, Universidad de Ingenieria y Tecnologia - UTEC, Jr. Medrano Silva 165, Barranco, Lima, Peru.
  • Monterrey C; Department of Electrical and Mechatronics Engineering, Universidad de Ingenieria y Tecnologia - UTEC, Jr. Medrano Silva 165, Barranco, Lima, Peru.
  • Mantari JL; Faculty of Mechanical Engineering, National University of Engineering, Av. Túpac Amaru 210, Rimac, Lima, Peru. Electronic address: jmantaril@uni.edu.pe.
  • Canahuire R; Department of Electrical and Mechatronics Engineering, Universidad de Ingenieria y Tecnologia - UTEC, Jr. Medrano Silva 165, Barranco, Lima, Peru.
  • Alvarez H; Department of Mechanical Engineering, Universidad de Ingenieria y Tecnologia - UTEC, Jr. Medrano Silva 165, Barranco, Lima, Peru. Electronic address: halvarez@utec.edu.pe.
  • Miranda M; Department of Mechanical Engineering, Universidad de Ingenieria y Tecnologia - UTEC, Jr. Medrano Silva 165, Barranco, Lima, Peru.
  • Elsheikh A; School of Engineering, University of Liverpool, UK.
J Biomech ; 118: 110234, 2021 03 30.
Article em En | MEDLINE | ID: mdl-33556888
This paper presents a computational and experimental analysis of a glaucoma flat drainage device (FDD). The FDD consists of a metallic microplate placed into the eye sclerocorneal limbus, which creates a virtual path between the anterior chamber and its exterior, allowing the intraocular pressure (IOP) to be kept in a normal range. It also uses the surrounding tissue as a flow regulator in order to provide close values of IOP for a wide range of aqueous humor (AH) flow rates. The Neo Hookean hyperelastic model is used for the solid part, while the Reynolds thin film fluid model is used for the fluid part. On the other hand, a gravitational-driven flow test is implemented in order to validate the simulation process. An in vitro experiment evaluated the flow characteristics of the device implanted in fourteen extirpated pig eyes, giving as a result the best-fit for the Young modulus of the tissue surrounding the device. Finally, according to the resulting computational model, for a range of 1.4-3.1 µL/min, the device presents a pressure variation range of 6-7.5 mmHg.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glaucoma / Implantes para Drenagem de Glaucoma Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Biomech Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Peru País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glaucoma / Implantes para Drenagem de Glaucoma Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Biomech Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Peru País de publicação: Estados Unidos