Squamous cell carcinoma mimics small cell carcinoma of the lung: a case report.

Kmeid, Michael; Gillie, Breanne; Asarian, Armand; Xiao, Philip

Kmeid, Michael; Gillie, Breanne; Asarian, Armand; Xiao, Philip.

Afiliação

Kmeid M; St George's University School of Medicine, True Blue, Grenada.
Gillie B; St George's University School of Medicine, True Blue, Grenada.
Asarian A; Department of Surgery, The Brooklyn Hospital Center, Icahn School of Medicine at Mount Sinai, Brooklyn, NY 11201, USA.
Xiao P; Department of Pathology, The Brooklyn Hospital Center, Icahn School of Medicine at Mount Sinai, Brooklyn, NY 11201, USA.

J Surg Case Rep ; 2020(12): rjaa531, 2020 Dec.

Article em En | MEDLINE | ID: mdl-33391656

RESUMO

Squamous cell carcinomas (SCC) accounts for roughly 20% of lung cancers in the USA. The 2015 World Health Organization classification of lung tumors further categorizes SCC as three subtypes: keratinizing, non-keratinizing and basaloid variant. The non-keratinizing subtype is a poorly differentiated tumor that can present histologically in different ways, and one of which is a rare variant that strongly resembles small cell carcinoma. As a result, histological diagnosis alone is not sufficient to properly diagnose lung carcinomas. Immunohistochemistry has been increasingly used over the past few years to differentiate between lung tumors. The combination of morphological and immunohistochemical staining should be the mainstay for diagnosis of all lung carcinomas as more targeted therapies become more available.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Surg Case Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Granada País de publicação: Reino Unido

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