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Chagas Disease Screening Using Point-of-Care Testing in an At-Risk Obstetric Population.
Zamora, Lindsey E; Palacio, Federico; Kozlowski, Debra S; Doraivelu, Kamini; Dude, Carolynn M; Jamieson, Denise J; Haddad, Lisa B.
Afiliação
  • Zamora LE; 1Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Palacio F; 2Division of Infectious Diseases, Department of Medicine, University of Cincinnati, Cincinnati, Ohio.
  • Kozlowski DS; 3Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
  • Doraivelu K; 3Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
  • Dude CM; 3Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
  • Jamieson DJ; 3Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
  • Haddad LB; 3Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
Am J Trop Med Hyg ; 104(3): 959-963, 2020 12 21.
Article em En | MEDLINE | ID: mdl-33350375
Congenital transmission is the most important mode of transmission of Chagas disease (CD) in non-endemic countries. Identifying CD in reproductive-aged women is essential to reduce the risk of transmitting the disease to their children and offer treatment to women and their children, which could cure the disease. We evaluated the use of point-of-care (POC) testing for CD in postpartum patients. In our patient population, 16.7% (23/138) tested positive by POC testing, but confirmatory testing was negative for all patients. Among those considered high risk, 30% declined participation. Our results suggest limited utility of the point-of-care test used in our study and identify an opportunity for improvement to broaden diagnostic testing options. Our study also highlights the need to develop strategies to increase subject participation in future research.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Chagas / Testes Imediatos Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Female / Humans / Pregnancy País/Região como assunto: America do norte / America do sul Idioma: En Revista: Am J Trop Med Hyg Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Chagas / Testes Imediatos Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Female / Humans / Pregnancy País/Região como assunto: America do norte / America do sul Idioma: En Revista: Am J Trop Med Hyg Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos