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Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.
Voysey, Merryn; Clemens, Sue Ann Costa; Madhi, Shabir A; Weckx, Lily Y; Folegatti, Pedro M; Aley, Parvinder K; Angus, Brian; Baillie, Vicky L; Barnabas, Shaun L; Bhorat, Qasim E; Bibi, Sagida; Briner, Carmen; Cicconi, Paola; Collins, Andrea M; Colin-Jones, Rachel; Cutland, Clare L; Darton, Thomas C; Dheda, Keertan; Duncan, Christopher J A; Emary, Katherine R W; Ewer, Katie J; Fairlie, Lee; Faust, Saul N; Feng, Shuo; Ferreira, Daniela M; Finn, Adam; Goodman, Anna L; Green, Catherine M; Green, Christopher A; Heath, Paul T; Hill, Catherine; Hill, Helen; Hirsch, Ian; Hodgson, Susanne H C; Izu, Alane; Jackson, Susan; Jenkin, Daniel; Joe, Carina C D; Kerridge, Simon; Koen, Anthonet; Kwatra, Gaurav; Lazarus, Rajeka; Lawrie, Alison M; Lelliott, Alice; Libri, Vincenzo; Lillie, Patrick J; Mallory, Raburn; Mendes, Ana V A; Milan, Eveline P; Minassian, Angela M.
Afiliação
  • Voysey M; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
  • Clemens SAC; Institute of Global Health, University of Siena, Siena, Brazil; Department of Paediatrics, University of Oxford, Oxford, UK.
  • Madhi SA; MRC Vaccines and Infectious Diseases Analytics Research Unit, Johannesburg, South Africa.
  • Weckx LY; Department of Pediatrics, Universidade Federal de São Paulo, São Paulo, Brazil.
  • Folegatti PM; Jenner Institute, Nuffield Department of Medicine, University of Oxford, UK.
  • Aley PK; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
  • Angus B; Jenner Institute, Nuffield Department of Medicine, University of Oxford, UK.
  • Baillie VL; Respiratory and Meningeal Pathogens Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
  • Barnabas SL; Family Centre for Research with Ubuntu, Department of Paediatrics, University of Stellenbosch, Cape Town, South Africa.
  • Bhorat QE; Soweto Clinical Trials Centre, Soweto, South Africa.
  • Bibi S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
  • Briner C; Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
  • Cicconi P; Jenner Institute, Nuffield Department of Medicine, University of Oxford, UK.
  • Collins AM; Department of Clinical Sciences, Liverpool School of Tropical Medicine and Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Colin-Jones R; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
  • Cutland CL; Respiratory and Meningeal Pathogens Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
  • Darton TC; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK; Department of Infection and Tropical Medicine, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
  • Dheda K; Division of Pulmonology, Groote Schuur Hospital and the University of Cape Town, South Africa; Faculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene & Tropical Medicine, London, UK.
  • Duncan CJA; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK; Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle University, Newcastle upon Tyne, UK.
  • Emary KRW; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
  • Ewer KJ; Jenner Institute, Nuffield Department of Medicine, University of Oxford, UK.
  • Fairlie L; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
  • Faust SN; NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK.
  • Feng S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
  • Ferreira DM; Department of Clinical Sciences, Liverpool School of Tropical Medicine and Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Finn A; School of Population Health Sciences, University of Bristol and University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
  • Goodman AL; Department of Infection, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London, UK; MRC Clinical Trials Unit, University College London, London, UK.
  • Green CM; Clinical BioManufacturing Facility, University of Oxford, Oxford, UK.
  • Green CA; NIHR/Wellcome Trust Clinical Research Facility, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
  • Heath PT; St George's Vaccine Institute, St George's, University of London, London, UK.
  • Hill C; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
  • Hill H; Department of Clinical Sciences, Liverpool School of Tropical Medicine and Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Hirsch I; AstraZeneca BioPharmaceuticals, Cambridge, UK.
  • Hodgson SHC; Jenner Institute, Nuffield Department of Medicine, University of Oxford, UK.
  • Izu A; VIDA-Vaccines and Infectious Diseases Analytical Research Unit, Johannesburg, South Africa.
  • Jackson S; Jenner Institute, Nuffield Department of Medicine, University of Oxford, UK.
  • Jenkin D; Jenner Institute, Nuffield Department of Medicine, University of Oxford, UK.
  • Joe CCD; Jenner Institute, Nuffield Department of Medicine, University of Oxford, UK.
  • Kerridge S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
  • Koen A; VIDA-Vaccines and Infectious Diseases Analytical Research Unit, Johannesburg, South Africa.
  • Kwatra G; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
  • Lazarus R; Severn Pathology, North Bristol NHS Trust, Bristol, UK.
  • Lawrie AM; Jenner Institute, Nuffield Department of Medicine, University of Oxford, UK.
  • Lelliott A; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
  • Libri V; NIHR UCLH Clinical Research Facility and NIHR UCLH Biomedical Research Centre, London, UK.
  • Lillie PJ; Department of Infection, Hull University Teaching Hospitals NHS Trust, UK.
  • Mallory R; AstraZeneca BioPharmaceuticals, Cambridge, UK.
  • Mendes AVA; Escola Bahiana de Medicina e Saúde Pública, Salvador, Braziland Hospital São Rafael, Salvador, Brazil; Instituto D'Or, Salvador, Brazil.
  • Milan EP; Department of Infectious Diseases, Universidade Federal do Rio Grande do Norte, Natal, Brazil.
  • Minassian AM; Jenner Institute, Nuffield Department of Medicine, University of Oxford, UK.
Lancet ; 397(10269): 99-111, 2021 01 09.
Article em En | MEDLINE | ID: mdl-33306989
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra COVID-19 / COVID-19 Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Africa / America do sul / Brasil / Europa Idioma: En Revista: Lancet Ano de publicação: 2021 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra COVID-19 / COVID-19 Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Africa / America do sul / Brasil / Europa Idioma: En Revista: Lancet Ano de publicação: 2021 Tipo de documento: Article País de publicação: Reino Unido