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COVID-19 and ethnicity: Does reduced responsiveness to glucocorticoids explain the more aggressive nature of disease among minorities?
Karan, Abhinav; Ali, Kabeer; Rambaran, Kirin; Del Corral, Pedro; Sakhamuri, Sateesh; Teelucksingh, Surujpal.
Afiliação
  • Karan A; Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
  • Ali K; Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
  • Rambaran K; Thoracic Medical Department, Caura Hospital, Trinidad and Tobago.
  • Del Corral P; Department of Physiology and Pathology, Burrell College of Osteopathic Medicine, Las Cruces, NM, USA.
  • Sakhamuri S; Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago. Electronic address: sateesh.sakhamuri@sta.uwi.edu.
  • Teelucksingh S; Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Med Hypotheses ; 144: 110220, 2020 Nov.
Article em En | MEDLINE | ID: mdl-33254527
Marked ethnic variations in complications and mortality have been noted following infection with COVID-19, with Black, Asian, and minority ethnic groups (BAME) being particularly hard hit. We hypothesise that glucocorticoid resistance stemming from several intrinsic reasons such as chronic social stress and lower circulating levels of Vitamin D may contribute to the exaggerated inflammatory response, more severe disease and poorer outcomes observed in BAME.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tratamento Farmacológico da COVID-19 / Glucocorticoides / Grupos Minoritários Tipo de estudo: Prognostic_studies Aspecto: Determinantes_sociais_saude Limite: Humans Idioma: En Revista: Med Hypotheses Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Trinidad e Tobago País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tratamento Farmacológico da COVID-19 / Glucocorticoides / Grupos Minoritários Tipo de estudo: Prognostic_studies Aspecto: Determinantes_sociais_saude Limite: Humans Idioma: En Revista: Med Hypotheses Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Trinidad e Tobago País de publicação: Estados Unidos