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Application of Artificial Intelligence Techniques for the Estimation of Basal Insulin in Patients with Type I Diabetes.
Guzman Gómez, Guillermo Edinson; Burbano Agredo, Luis Eduardo; Martínez, Veline; Bedoya Leiva, Oscar Fernando.
Afiliação
  • Guzman Gómez GE; Fundación Valle del Lili, Departamento de Endocrinología, Cali, Colombia.
  • Burbano Agredo LE; Universidad Icesi, Facultad de Ciencias de la Salud, Cali, Colombia.
  • Martínez V; Universidad del Valle, Cali, Colombia.
  • Bedoya Leiva OF; Universidad Icesi, Facultad de Ciencias de la Salud, Cali, Colombia.
Int J Endocrinol ; 2020: 7326073, 2020.
Article em En | MEDLINE | ID: mdl-33204261
Artificial intelligence techniques have been positioned in the resolution of problems in various areas of healthcare. Clinical decision support systems developed from this technology have optimized the healthcare of patients with chronic diseases through mobile applications. In this study, several models based on this methodology have been developed to calculate the basal insulin dose in patients with type I diabetes using subcutaneous insulin infusion pumps. Methods. A pilot experimental study was performed with data from 56 patients with type 1 diabetes who used insulin infusion pumps and underwent continuous glucose monitoring. Several models based on artificial intelligence techniques were developed to analyze glycemic patterns based on continuous glucose monitoring and clinical variables in order to estimate the basal insulin dose. We used neural networks (NNs), Bayesian networks (BNs), support vector machines (SVMs), and random forests (RF). We then evaluated the agreement between predicted and actual values using several statistical error measurements: mean absolute error (MAE), mean square error (MSE), root-mean-square error (RMSE), Pearson's correlation coefficient (R), and determination coefficient (R 2). Results. Twenty-four different models were obtained, one for each hour of the day, with each chosen technique. Correlation coefficients obtained with RF, SVMs, NNs, and BNs were 0.9999, 0.9921, 0.0303, and 0.7754, respectively. The error increased between 06:00 and 07:00 and between 13:00 and 17:00. Conclusions. The performance of the RF technique was excellent and got very close to the actual values. Intelligence techniques could be used to predict basal insulin dose. However, it is necessary to explore the validity of the results and select the target population. Models that allow for more accurate levels of prediction should be further explored.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Int J Endocrinol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Egito

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Int J Endocrinol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Egito