Is the Frequency of Candidemia Increasing in COVID-19 Patients Receiving Corticosteroids?

Riche, Cezar V W; Cassol, Renato; Pasqualotto, Alessandro C

Riche, Cezar V W; Cassol, Renato; Pasqualotto, Alessandro C.

Afiliação

Riche CVW; Hospital Ernesto Dornelles, Porto Alegre 90160-092, Brazil.
Cassol R; School of Medicine, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre 90050-170, Brazil.
Pasqualotto AC; Hospital Nossa Senhora da Conceição, Porto Alegre 91350-200, Brazil.

J Fungi (Basel) ; 6(4)2020 Nov 13.

Article em En | MEDLINE | ID: mdl-33203016

RESUMO

Corticosteroids have potent anti-inflammatory and immunosuppressive effects. Recently, these medications have gained importance in the treatment of severe COVID-19. Here we present data demonstrating a marked (10-fold) increase in frequency of candidemia in hospitalized patients with COVID-19 receiving corticosteroids in Brazil. Overall mortality was 72.7%, despite antifungal therapy. Physicians should be aware of the potential risk for candidemia among severely ill COVID-19 patients receiving high-doses of corticosteroids.

Palavras-chave

COVID-19; candidemia; steroids

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Fungi (Basel) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

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