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Predicting the risk of future depression among school-attending adolescents in Nigeria using a model developed in Brazil.
Brathwaite, Rachel; Rocha, Thiago Botter-Maio; Kieling, Christian; Kohrt, Brandon A; Mondelli, Valeria; Adewuya, Abiodun O; Fisher, Helen L.
Afiliação
  • Brathwaite R; King's College London, Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, United Kingdom.
  • Rocha TB; Department of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Child & Adolescent Psychiatry Division, Hospital de Clínicas de Porto Alegre, Brazil.
  • Kieling C; Department of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Child & Adolescent Psychiatry Division, Hospital de Clínicas de Porto Alegre, Brazil.
  • Kohrt BA; Division of Global Mental Health, George Washington University, Washington DC, United States.
  • Mondelli V; King's College London, Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, London, United Kingdom; National Institute for Health Research Mental Health Biomedical Research Centre, South London and Maudsley NHS Foundation Trust and King's College London, Lond
  • Adewuya AO; Department of Behavioural Medicine, Lagos State University College of Medicine, Lagos, Nigeria; Centre for Mental Health Research and Initiative (CEMHRI), Lagos, Nigeria.
  • Fisher HL; King's College London, Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, United Kingdom; ESRC Centre for Society and Mental Health, King's College London, London, United Kingdom. Electronic address: helen.2.fisher@kcl.ac.uk.
Psychiatry Res ; 294: 113511, 2020 12.
Article em En | MEDLINE | ID: mdl-33113451
Depression commonly emerges in adolescence and is a major public health issue in low- and middle-income countries where 90% of the world's adolescents live. Thus efforts to prevent depression onset are crucial in countries like Nigeria, where two-thirds of the population are aged under 24. Therefore, we tested the ability of a prediction model developed in Brazil to predict future depression in a Nigerian adolescent sample. Data were obtained from school students aged 14-16 years in Lagos, who were assessed in 2016 and 2019 for depression using a self-completed version of the Mini International Neuropsychiatric Interview for Children and Adolescents. Only the 1,928 students free of depression at baseline were included. Penalized logistic regression was used to predict individualized risk of developing depression at follow-up for each adolescent based on the 7 matching baseline sociodemographic predictors from the Brazilian model. Discrimination between adolescents who did and did not develop depression was better than chance (area under the curve = 0.62 (bootstrap-corrected 95% CI: 0.58-0.66). However, the model was not well-calibrated even after adjustment of the intercept, indicating poorer overall performance compared to the original Brazilian cohort. Updating the model with context-specific factors may improve prediction of depression in this setting.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Instituições Acadêmicas / Estudantes / Inquéritos Epidemiológicos / Comportamento do Adolescente / Depressão Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Limite: Adolescent / Female / Humans / Male País/Região como assunto: Africa / America do sul / Brasil Idioma: En Revista: Psychiatry Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Irlanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Instituições Acadêmicas / Estudantes / Inquéritos Epidemiológicos / Comportamento do Adolescente / Depressão Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Limite: Adolescent / Female / Humans / Male País/Região como assunto: Africa / America do sul / Brasil Idioma: En Revista: Psychiatry Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Irlanda