Your browser doesn't support javascript.
loading
Appraising the effectiveness of electrical and magnetic brain stimulation techniques in acute major depressive episodes: an umbrella review of meta-analyses of randomized controlled trials.
Razza, Laís B; Afonso Dos Santos, Leonardo; Borrione, Lucas; Bellini, Helena; Branco, Luis C; Cretaz, Eric; Duarte, Dante; Ferrão, Ygor; Galhardoni, Ricardo; Quevedo, João; Simis, Marcel; Fregni, Felipe; Correll, Christoph U; Padberg, Frank; Trevizol, Alisson; Daskalakis, Zafiris J; Carvalho, Andre F; Solmi, Marco; Brunoni, André R.
Afiliação
  • Razza LB; Serviço Interdisciplinar de Neuromodulação, Laboratório de Neurociências (LIM27), Departamento e Instituto de Psiquiatria, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.
  • Afonso Dos Santos L; Serviço Interdisciplinar de Neuromodulação, Laboratório de Neurociências (LIM27), Departamento e Instituto de Psiquiatria, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.
  • Borrione L; Serviço Interdisciplinar de Neuromodulação, Laboratório de Neurociências (LIM27), Departamento e Instituto de Psiquiatria, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.
  • Bellini H; Serviço Interdisciplinar de Neuromodulação, Laboratório de Neurociências (LIM27), Departamento e Instituto de Psiquiatria, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.
  • Branco LC; Laboratório de Neuroimagem em Psiquiatria (LIM21), Departamento e Instituto de Psiquiatria, HCFMUSP, São Paulo, SP, Brazil.
  • Cretaz E; Neuromodulation and Clinical Research Center, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA, USA.
  • Duarte D; Serviço de Eletroconvulsoterapia, Departamento e Instituto de Psiquiatria, HCFMUSP, São Paulo, SP, Brazil.
  • Ferrão Y; Neuromodulation and Clinical Research Center, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA, USA.
  • Galhardoni R; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
  • Quevedo J; Departamento de Clínica Médica, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil.
  • Simis M; Faculdade de Medicina, Universidade Cidade de São Paulo (UNICID), São Paulo, SP, Brazil.
  • Fregni F; Centro de Dor (LIM-62), Departamento de Neurologia, HCFMUSP, São Paulo, SP, Brazil.
  • Correll CU; Translational Psychiatry Program, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.
  • Padberg F; Center of Excellence on Mood Disorders, Faillace Department of Psychiatry and Behavioral Sciences, UTHealth, McGovern Medical School, Houston, TX, USA.
  • Trevizol A; Neuroscience Graduate Program, The University of Texas, MD Anderson Cancer Center, UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA.
  • Daskalakis ZJ; Laboratório de Psiquiatria Translacional, Programa de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil.
  • Carvalho AF; Instituto de Medicina Física e Reabilitação, HCFMUSP, São Paulo, SP, Brazil.
  • Solmi M; Laboratory of Neuromodulation & Center for Clinical Research Learning, Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA, USA.
  • Brunoni AR; Department of Psychiatry, The Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, USA.
Braz J Psychiatry ; 43(5): 514-524, 2021.
Article em En | MEDLINE | ID: mdl-33111776
Electrical and magnetic brain stimulation techniques present distinct mechanisms and efficacy in the acute treatment of depression. This was an umbrella review of meta-analyses of randomized controlled trials of brain stimulation techniques for managing acute major depressive episodes. A systematic review was performed in the PubMed/MEDLINE databases from inception until March 2020. We included the English language meta-analysis with the most randomized controlled trials on the effects of any brain stimulation technique vs. control in adults with an acute depressive episode. Continuous and dichotomous outcomes were assessed. A Measurement Tool to Assess Systematic Reviews-2 was applied and the credibility of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation framework. Seven meta-analyses were included (5,615 patients), providing evidence for different modalities of brain stimulation techniques. Three meta-analyses were evaluated as having high methodological quality, three as moderate, and one as low. The highest quality of evidence was found for high frequency-repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation, and bilateral rTMS. There is strong clinical research evidence to guide future clinical use of some techniques. Our results confirm the heterogeneity of the effects across these techniques, indicating that different mechanisms of action lead to different efficacy profiles.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Depressivo Maior / Estimulação Transcraniana por Corrente Contínua Tipo de estudo: Clinical_trials / Guideline / Systematic_reviews Limite: Adult / Humans Idioma: En Revista: Braz J Psychiatry Assunto da revista: PSIQUIATRIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Depressivo Maior / Estimulação Transcraniana por Corrente Contínua Tipo de estudo: Clinical_trials / Guideline / Systematic_reviews Limite: Adult / Humans Idioma: En Revista: Braz J Psychiatry Assunto da revista: PSIQUIATRIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil