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First record of natural infection by Angiostrongylus cantonensis (Nematoda: Metastrongyloidea) in Belocaulus willibaldoi and Rattus norvegicus in an urban area of São Paulo city, SP, Brazil.
da Mota, Dan Jessé Gonçalves; de Melo, Leyva Cecilia Vieira; Pereira-Chioccola, Vera Lúcia; Gava, Ricardo; Pinto, Pedro Luiz Silva.
Afiliação
  • da Mota DJG; Secretaria Municipal da Saúde de São Paulo- (UVIS Parelheiros) - Departamento de Vigilância Sanitária, Rua Cristina Schunck Klein, 23, CEP: 04890-350, São Paulo, SP, Brazil.
  • de Melo LCV; Núcleo de Enteroparasitas, Instituto Adolfo Lutz, Avenida Doutor Arnaldo, 355- 8º andar- CEP: 01246-000, São Paulo, SP, Brazil.
  • Pereira-Chioccola VL; Laboratório de Biologia Molecular de Parasitas e Fungos, Instituto Adolfo Lutz, Avenida Doutor Arnaldo, 355 - 8º andar- CEP: 01246-000, São Paulo, SP, Brazil.
  • Gava R; Laboratório de Biologia Molecular de Parasitas e Fungos, Instituto Adolfo Lutz, Avenida Doutor Arnaldo, 355 - 8º andar- CEP: 01246-000, São Paulo, SP, Brazil.
  • Pinto PLS; Núcleo de Enteroparasitas, Instituto Adolfo Lutz, Avenida Doutor Arnaldo, 355- 8º andar- CEP: 01246-000, São Paulo, SP, Brazil.
Heliyon ; 6(10): e05150, 2020 Oct.
Article em En | MEDLINE | ID: mdl-33083611
Angiostrongylus cantonensis, a rat lungworm, is one of the leading causes of eosinophilic meningitis in humans. Infection in humans occurs by the ingestion of intermediate hosts, undercooked paratenic hosts or contaminated vegetables and fruits by mucus from infected molluscs. This zoonosis is widespread in tropical and subtropical areas of Southeast Asia, it has also been reported in the Pacific Islands as well as in other regions of Americas. In Brazil, human cases of angiostrongyliasis have been reported since 2007 in Southeast, Northeast, and South regions. In January 2011, we collected a batch of 30 Belocaulus willibaldoi slides in a neighborhood of São Paulo city (Parque Fernanda). Six of them were used for identifying species, and the others (24) were used in parasitological tests through digestion in peptic solution and then larvae isolation by the Rugai method. A total of 250 larvae were obtained and they had morphological traits of Angiostrongylus spp. Later, four Golden hamsters (Mesocricetus auratus) were infected with 38 larvae that allowed the recovery of young worms from the brain and lungs of rodents on the 21st and 30th day of infection. In this same neighborhood we captured rodents (Rattus norvegicus) that, after necropsy led us to recovery of 22 adult worms in the pulmonary arteries (14 males and 8 females) in May 2011. The larvae and worms obtained from natural infection were evaluated by morphological and morphometric parameters, as well as biological behavior patterns and molecular profile. All methodologies identified the parasite as Angiostrongylus cantonensis. In this way, we report for the first time, the natural infection by A. cantonensis in intermediate (B. willibaldoi) and definitive (R. norvegicus) hosts in a new urban region of Brazil.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: America do sul / Brasil Idioma: En Revista: Heliyon Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: America do sul / Brasil Idioma: En Revista: Heliyon Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido