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Hereditary angioedema: Report of the dental treatment of 12 Brazilian patients.
Lima, Bernardo Correia; Ragon, Claudia de S Thiago; Veras, Rafaela Alves; Gomes, Alessandra Oliveira Ferrari; Alonso, Maria Luiza Oliva; Valle, Solange Oliveira Rodrigues; Torres, Sandra Regina; Agostini, Michelle.
Afiliação
  • Lima BC; Department of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
  • Ragon CST; Clinical Dentistry Service, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro, Brazil.
  • Veras RA; Department of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
  • Gomes AOF; Clinical Dentistry Service, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro, Brazil.
  • Alonso MLO; Department of Internal Medicine, Immunology Service, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro, School of Medicine, Rio de Janeiro, Brazil.
  • Valle SOR; Department of Internal Medicine, Immunology Service, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro, School of Medicine, Rio de Janeiro, Brazil.
  • Torres SR; Department of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil; Clinical Dentistry Service, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro, Brazil.
  • Agostini M; Department of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil; Clinical Dentistry Service, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro, Brazil. Electronic address: Michellegostini@odonto.uf
Oral Surg Oral Med Oral Pathol Oral Radiol ; 130(6): 651-658, 2020 Dec.
Article em En | MEDLINE | ID: mdl-33012673
OBJECTIVE: The aim of this study was to report on clinical experience in Brazil in the dental treatment and the oral conditions of a group of patients with hereditary angioedema (HAE). STUDY DESIGN: The study analyzed demographic data, type of HAE, intensity of attacks, long-term and short-term prophylaxis, dental procedures, and occurrence of crises after the procedures were performed. Radiographic evaluation of the number of teeth and bone loss was also performed. RESULTS: Data from 12 patients were collected; most were women, presenting with C1-INH-HAE type I and a history of severe attacks. All patients reported use of regular medications (long-term prophylaxis), mostly attenuated androgens, to prevent/attenuate HAE attacks. These patients had several missing teeth and alveolar bone loss. Tooth extraction was the most common procedure. In half the patients, the procedures had been performed without modification in long-term prophylaxis. The others were treated with an additional prophylaxis protocol (short-term prophylaxis), particularly those who underwent tooth extraction. None of the study patients developed HAE attacks after dental procedures. CONCLUSION: The occurrence and intensity of a possible HAE attack after dental procedures are unpredictable, but with careful preliminary screening by dental and immunology teams and the use of therapeutic prophylaxis, the risk could be minimized.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Angioedemas Hereditários Tipo de estudo: Guideline Limite: Female / Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Angioedemas Hereditários Tipo de estudo: Guideline Limite: Female / Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos