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The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway.
Spagnol, Valentine; Oliveira, Caio A B; Randle, Suzanne J; Passos, Patrícia M S; Correia, Camila R S T B; Simaroli, Natália B; Oliveira, Joice S; Mevissen, Tycho E T; Medeiros, Ana Carla; Gomes, Marcelo D; Komander, David; Laman, Heike; Teixeira, Felipe Roberti.
Afiliação
  • Spagnol V; Department of Genetics and Evolution, Federal University of Sao Carlos, Brazil.
  • Oliveira CAB; Department of Genetics and Evolution, Federal University of Sao Carlos, Brazil.
  • Randle SJ; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.
  • Passos PMS; Department of Genetics and Evolution, Federal University of Sao Carlos, Brazil.
  • Correia CRSTB; Department of Genetics and Evolution, Federal University of Sao Carlos, Brazil.
  • Simaroli NB; Department of Genetics and Evolution, Federal University of Sao Carlos, Brazil.
  • Oliveira JS; Department of Genetics and Evolution, Federal University of Sao Carlos, Brazil.
  • Mevissen TET; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK; Harvard Medical School, Department of Biological Chemistry and Molecular Pharmacology, 250 Longwood Ave, Boston, MA 02115, USA.
  • Medeiros AC; Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, Brazil.
  • Gomes MD; Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, Brazil.
  • Komander D; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK; The Walter and Eliza Hall Institute of Medical Research, Ubiquitin Signalling Division, 1G Royal Parade, Parkville 3052, VIC, Australia.
  • Laman H; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.
  • Teixeira FR; Department of Genetics and Evolution, Federal University of Sao Carlos, Brazil. Electronic address: frt@ufscar.br.
Biochim Biophys Acta Gen Subj ; 1865(1): 129754, 2021 01.
Article em En | MEDLINE | ID: mdl-33010352
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / NF-kappa B / Chaperonas Moleculares / Proteínas de Ciclo Celular / Proteínas Ligases SKP Culina F-Box / Proteínas F-Box Limite: Humans Idioma: En Revista: Biochim Biophys Acta Gen Subj Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / NF-kappa B / Chaperonas Moleculares / Proteínas de Ciclo Celular / Proteínas Ligases SKP Culina F-Box / Proteínas F-Box Limite: Humans Idioma: En Revista: Biochim Biophys Acta Gen Subj Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda