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Sustained reduction of healthcare-associated infections after the introduction of a bundle for prevention of ventilator-associated pneumonia in medical-surgical intensive care units.
Fortaleza, Carlos Magno Castelo Branco; Filho, Sebastião Pires Ferreira; Silva, Marina de Oliveira; Queiroz, Sandra Mara; Cavalcante, Ricardo de Souza.
Afiliação
  • Fortaleza CMCB; Universidade do Estado de São Paulo(UNESP), Faculdade de Medicina de Botucatu, Department of Infectious Diseases, Botucatu, SP, Brazil. Electronic address: carlos.fortaleza@unesp.br.
  • Filho SPF; Universidade do Estado de São Paulo(UNESP), Faculdade de Medicina de Botucatu, Department of Infectious Diseases, Botucatu, SP, Brazil.
  • Silva MO; Universidade do Estado de São Paulo(UNESP), Faculdade de Medicina de Botucatu, Department of Infectious Diseases, Botucatu, SP, Brazil.
  • Queiroz SM; Universidade do Estado de São Paulo(UNESP), Faculdade de Medicina de Botucatu, Department of Infectious Diseases, Botucatu, SP, Brazil.
  • Cavalcante RS; Universidade do Estado de São Paulo(UNESP), Faculdade de Medicina de Botucatu, Department of Infectious Diseases, Botucatu, SP, Brazil.
Braz J Infect Dis ; 24(5): 373-379, 2020.
Article em En | MEDLINE | ID: mdl-32949494
BACKGROUND: Infection control interventions can be erroneously interpreted if outcomes are assessed in short periods. Also, statistical methods usually applied to compare outcomes before and after interventions are not appropriate for analyzing time series. AIMS: To analyze the impact of a bundle directed at reducing the incidence of ventilator-associated pneumonia (VAP) and other device-associated infections in two medical-surgical intensive care units (ICU) in Brazil. METHODS: Our study had a quasi-experimental design. Interrupted time series analyses (ITS) was performed assessing monthly rates of overall healthcare-associated infections (HCAI), VAP, laboratory-confirmed central line associated bloodstream infections (CLABSI) and catheter-associated urinary tract infections (CAUTI), from January 2007 through June 2019. Moreover, multivariate ITS was adjusted for seasonality in Poisson regression models. An intervention based on a bundle for VAP prevention was introduced in August 2010. FINDINGS: The intervention was followed by sustained reduction in overall HCAI, VAP and CLABSI in both ICU. Continuous post-intervention trends towards reduction were detected for overall HCAI and VAP. CONCLUSION: Interventions aimed at preventing one specific site of infection may have sustained impact on other HCAI, which can be documented using time series analyses.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecção Hospitalar / Pneumonia Associada à Ventilação Mecânica / Infecções Relacionadas a Cateter Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Braz J Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2020 Tipo de documento: Article País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecção Hospitalar / Pneumonia Associada à Ventilação Mecânica / Infecções Relacionadas a Cateter Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Braz J Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2020 Tipo de documento: Article País de publicação: Brasil