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Effect of COVID-19 on platelet count and its indices.
Güçlü, Ertugrul; Kocayigit, Havva; Okan, Hüseyin Dogus; Erkorkmaz, Unal; Yürümez, Yusuf; Yaylaci, Selcuk; Koroglu, Mehmet; Uzun, Cem; Karabay, Oguz.
Afiliação
  • Güçlü E; . Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya, Turkey.
  • Kocayigit H; . Sakarya University Training and Research Hospital, Division of Anesthesiology, Sakarya, Turkey.
  • Okan HD; . Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya, Turkey.
  • Erkorkmaz U; . Sakarya University Faculty of Medicine, Department of Biostatistics, Sakarya, Turkey.
  • Yürümez Y; . Sakarya University Faculty of Medicine, Department of Emergency Medicine, Sakarya, Turkey.
  • Yaylaci S; . Sakarya University Faculty of Medicine, Department of Internal Medicine, Sakarya, Turkey.
  • Koroglu M; . Sakarya University Faculty of Medicine, Department of Medical Microbiology, Sakarya, Turkey.
  • Uzun C; . Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya, Turkey.
  • Karabay O; . Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya, Turkey.
Rev Assoc Med Bras (1992) ; 66(8): 1122-1127, 2020 Aug.
Article em En | MEDLINE | ID: mdl-32935808
BACKGROUND: Easily accessible, inexpensive, and widely used laboratory tests that demonstrate the severity of COVID-19 are important. Therefore, in this study, we aimed to investigate the relationship between mortality in COVID-19 and platelet count, Mean Platelet Volume (MPV), and platelet distribution width. METHODS: In total, 215 COVID-19 patients were included in this study. The patients were divided into two groups. Patients with room air oxygen saturation < 90% were considered as severe COVID-19, and patients with ≥90% were considered moderate COVID-19. Patient medical records and the electronic patient data monitoring system were examined retrospectively. Analyses were performed using the SPSS statistical software. A p-value <0.05 was considered significant. RESULTS: The patients' mean age was 64,32 ± 16,07 years. According to oxygen saturation, 81 patients had moderate and 134 had severe COVID-19. Our findings revealed that oxygen saturation at admission and the MPV difference between the first and third days of hospitalization were significant parameters in COVID-19 patients for predicting mortality. While mortality was 8.4 times higher in patients who had oxygen saturation under 90 % at hospital admission, 1 unit increase in MPV increased mortality 1.76 times. CONCLUSION: In addition to the lung capacity of patients, the mean platelet volume may be used as an auxiliary test in predicting the mortality in COVID-19 patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Pandemias / Betacoronavirus Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Humans / Middle aged Idioma: En Revista: Rev Assoc Med Bras (1992) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Turquia País de publicação: Brasil
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Pandemias / Betacoronavirus Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Humans / Middle aged Idioma: En Revista: Rev Assoc Med Bras (1992) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Turquia País de publicação: Brasil