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ARE OBESITY AND ADENOMA DEVELOPMENT ASSOCIATED AS COLORECTAL CANCER PRECURSORS?
Freitas, Bianca Astrogildo de; Loth, Carlos Alberto Tomatis; Swarowsky, Gustavo Lazaroto; LourenÇo, Graziela Morais; Fillmann, Lucio Sarubbi; Fillmann, Henrique Sarubbi; Santos, Maria Luiza; Padoin, Alexandre Vontobel.
Afiliação
  • Freitas BA; Pontifical University do Rio Grande do Sul, School of Medicine, Porto Alegre, RS, Brazil.
  • Loth CAT; Faculty of Medicine, Federal University of Rio Grande, Rio Grande, RS, Brazil.
  • Swarowsky GL; Pontifical University do Rio Grande do Sul, School of Medicine, Porto Alegre, RS, Brazil.
  • LourenÇo GM; Pontifical University do Rio Grande do Sul, School of Medicine, Porto Alegre, RS, Brazil.
  • Fillmann LS; Pontifical University do Rio Grande do Sul, School of Medicine, Porto Alegre, RS, Brazil.
  • Fillmann HS; Pontifical University do Rio Grande do Sul, School of Medicine, Porto Alegre, RS, Brazil.
  • Santos ML; Pontifical University do Rio Grande do Sul, School of Medicine, Porto Alegre, RS, Brazil.
  • Padoin AV; Pontifical University do Rio Grande do Sul, School of Medicine, Porto Alegre, RS, Brazil.
Arq Bras Cir Dig ; 33(1): e1500, 2020 Jul 08.
Article em En, Pt | MEDLINE | ID: mdl-32667530
BACKGROUND: One of the most important concerns on health is the increased rates of obesity in population and the speed in which this number is increasing. This number translates a serious public health problem, since it also increases the risk of several other diseases associated with obesity resulting in significant morbidity and mortality. Among them, it seems to be connected to several neoplasms, such as colorectal carcinoma. AIM: To evaluate the impact of obesity as a risk factor for colorectal carcinoma through the detection of adenoma, and to discuss the mechanisms that could establish a link between obesity and neoplasm. METHODS: Patients who underwent colonoscopy were included. Personal and anthropometric data, clinical history, and results of the tests were analyzed in order to verify the correlation of BMI and the presence of adenomatous polyps. RESULTS: A total of 142 patients were studied, which a mean age of 62 years. Of the patients, 74 (52.1%) were men and 68 (47.9%) were. Obesity was identified in 16.2% of the patients. Polyps were found in 61 (42.9%), mostly smaller than 1 cm. Obese individuals were 1.56 times more likely to present colorectal adenoma than patients with normal weight. CONCLUSION: This study, although showing the greater presence of colorectal adenomas in obese individuals, did not show a significant difference in the occurrence of pre-malignant lesions.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Adenoma Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En / Pt Revista: Arq Bras Cir Dig Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Adenoma Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En / Pt Revista: Arq Bras Cir Dig Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil