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Low calf circumference is an independent predictor of mortality in cancer patients: A prospective cohort study.
Sousa, Iasmin Matias; Bielemann, Renata Moraes; Gonzalez, Maria Cristina; da Rocha, Ilanna Marques Gomes; Barbalho, Erica Roberta; de Carvalho, Ana Lúcia Miranda; Dantas, Maria Amélia Marques; de Medeiros, Galtieri Otávio Cunha; Silva, Flavia Moraes; Fayh, Ana Paula Trussardi.
Afiliação
  • Sousa IM; Postgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Brazil.
  • Bielemann RM; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.
  • Gonzalez MC; Postgraduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas, Brazil.
  • da Rocha IMG; Postgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Brazil.
  • Barbalho ER; Postgraduate Program in Physical Education, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Brazil.
  • de Carvalho ALM; Postgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Brazil.
  • Dantas MAM; Liga Norteriograndense Contra Câncer, Natal, Brazil.
  • de Medeiros GOC; Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, Natal, Brazil.
  • Silva FM; Postgraduate Program in Nutrition Science, Federal University of Health Science of Porto Alegre, Porto Alegre, Brazil.
  • Fayh APT; Postgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Brazil; Postgraduate Program in Physical Education, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Brazil. Electronic address: apfayh@yahoo.com.br.
Nutrition ; 79-80: 110816, 2020.
Article em En | MEDLINE | ID: mdl-32569952
OBJECTIVE: Loss of muscle mass is associated with worse outcomes in patients with cancer. The objective of this study was to evaluate the prognostic value of calf circumference (CC) and skeletal muscle index from computed tomography (CT) to predict mortality in patients with cancer. METHODS: A single-center prospective study was conducted with patients aged ≥20 y attending a reference center of oncology and who had recent abdominal CT images. Data were collected through a semistructured form and patients' records and included sociodemographic data (sex, age and ethnicity), clinical data (primary site and staging of tumor and treatments performed), anthropometric variables (body mass index and CC), and outcome (death). Low CC for men was considered to be ≤ 34 cm and for women ≤ 33 cm. Muscle mass was assessed by CT images at the level of L3. The Cox proportional hazard model adjusted for age, sex, and staging of disease was used. RESULTS: A total of 250 patients were evaluated, 52.8% female, with a median age of 63 y (interquartile ratio: 55-73). Normal body mass index was identified in 44.4%; 29.2% had low skeletal muscle index, and 46.4% had low CC. Death by any cause occurred in 16%, and only low CC was a significant predictor of mortality (hazard ratio = 3.01; confidence interval 1.52-5.98; P = 0.002). CONCLUSIONS: Low CC can predict risk of mortality in this cohort of patients. The findings suggest the use of CC as a simple, easy, cost-effective anthropometric measurement to quickly screen patients at risk of death who could benefit from targeted care to improve their prognosis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Perna (Membro) / Neoplasias Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Nutrition Assunto da revista: CIENCIAS DA NUTRICAO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Perna (Membro) / Neoplasias Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Nutrition Assunto da revista: CIENCIAS DA NUTRICAO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos