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Multicenter Analysis of Acquired Undescended Testis and Its Impact on the Timing of Orchidopexy.
Boehme, Philip; Degener, Stephan; Wirth, Stefan; Geis, Berit; Aydin, Malik; Lawrenz, Karin; Troebs, Ralf-Bodo; Schmittenbecher, Peter; Beume, Jan; Pötzsch, Simone; Schwarz, Beate; Hensel, Kai O.
Afiliação
  • Boehme P; Center for Clinical and Translational Research, Department of Pediatrics, Helios University Hospital Wuppertal, Faculty of Health, Witten/Herdecke University, Wuppertal, Germany; Cardiovascular Research, Bayer Pharma, Wuppertal, Germany.
  • Degener S; Center for Clinical and Translational Research, Department of Urology, Helios University Hospital Wuppertal, Faculty of Health, Witten/Herdecke University, Wuppertal, Germany.
  • Wirth S; Center for Clinical and Translational Research, Department of Pediatrics, Helios University Hospital Wuppertal, Faculty of Health, Witten/Herdecke University, Wuppertal, Germany.
  • Geis B; Institute of Medical Biometry and Epidemiology, Faculty of Health, Witten/Herdecke University, Witten, Germany.
  • Aydin M; Center for Clinical and Translational Research, Department of Pediatrics, Helios University Hospital Wuppertal, Faculty of Health, Witten/Herdecke University, Wuppertal, Germany.
  • Lawrenz K; Department for Pediatric Surgery and Pediatric Urology, Helios Hospital Krefeld, Krefeld, Germany.
  • Troebs RB; Department for Pediatric Surgery, Marien Hospital Herne, University of Bochum, Bochum, Germany.
  • Schmittenbecher P; Department for Pediatric Surgery, City Hospital Karlsruhe, Karlsruhe, Germany.
  • Beume J; Department for Pediatric Surgery, City Hospital Karlsruhe, Karlsruhe, Germany.
  • Pötzsch S; Department of Pediatrics, Helios Hospital Plauen, Plauen, Germany.
  • Schwarz B; Department of Pediatrics, Helios Hospital Bad Saarow, Bad Saarow, Germany.
  • Hensel KO; Center for Clinical and Translational Research, Department of Pediatrics, Helios University Hospital Wuppertal, Faculty of Health, Witten/Herdecke University, Wuppertal, Germany; Department of Pediatrics, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge Biomedic
J Pediatr ; 223: 170-177.e3, 2020 08.
Article em En | MEDLINE | ID: mdl-32532648
OBJECTIVE: To assess whether late orchidopexy for undescended testis represents delayed treatment of primary undescended testis or later-occurring acquired undescended testis. STUDY DESIGN: We examined boys undergoing orchidopexy for cryptorchidism regarding age at surgery and entity of undescended testis. We characterized differences between primary undescended testis and acquired undescended testis and evaluated the knowledge regarding the diagnosis and management of acquired undescended testis among practicing physicians. We conducted an observational study using a mixed-method multicenter cross-sectional design. A total of 310 consecutive boys undergoing orchidopexy for undescended testis at 6 pediatric medical centers in Germany between April 2016 and June 2018 were investigated regarding testicular position at birth and age at surgery. In addition, a survey on acquired undescended testis management was carried out in 1017 multidisciplinary physicians and final-year medical students. RESULTS: Only 13% of all patients were operated on in their first year of life. Among patients with known previous testicular position (67%), primary undescended testis (n = 103) and acquired undescended testis (n = 104) were equally frequent. More than one-half (56%) of orchidopexies performed after the first year of life were due to acquired undescended testis. Remarkably, only 15% of physicians considered acquired undescended testis as an indication for late surgery. CONCLUSIONS: Acquired undescended testis is more common than previously perceived and accounts for a significant proportion of "late" orchidopexies in patients with undescended testis. Acquired undescended testis needs to be better recognized in clinical practice and screening should continue in older children with previously descended testes. TRIAL REGISTRATION: German Clinical Trials Registry: DRKS00015903.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Criptorquidismo / Orquidopexia Tipo de estudo: Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Child, preschool / Humans / Male País/Região como assunto: Europa Idioma: En Revista: J Pediatr Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Criptorquidismo / Orquidopexia Tipo de estudo: Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Child, preschool / Humans / Male País/Região como assunto: Europa Idioma: En Revista: J Pediatr Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos