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Calcium Bioavailability of Opuntia ficus-indica Cladodes in an Ovariectomized Rat Model of Postmenopausal Bone Loss.
Quintero-García, Michelle; Gutiérrez-Cortez, Elsa; Rojas-Molina, Alejandra; Mendoza-Ávila, Monsserrat; Del Real, Alicia; Rubio, Efraín; Jiménez-Mendoza, Daniel; Rojas-Molina, Isela.
Afiliação
  • Quintero-García M; Programa de Maestría en Ciencias Químico Biológicas, Facultad de Química, Universidad Autónoma de Querétaro, Cerro de las Campanas S/N, C.P. 76010 Querétaro, Mexico.
  • Gutiérrez-Cortez E; Laboratorio de Química Medicinal, Facultad de Química, Universidad Autónoma de Querétaro, Cerro de las Campanas S/N, C.P. 76010 Querétaro, Mexico.
  • Rojas-Molina A; Laboratorio de procesos de transformación y tecnologías emergentes en alimentos, Facultad de Estudios Superiores-Cuautitlán, Universidad Nacional Autónoma de México, Km 2.5 Carretera Cuautitlán-Teoloyucan, San Sebastián Xhala, C.P. 54714, Cuautitlán-Izcalli, Mexico.
  • Mendoza-Ávila M; Laboratorio de Química Medicinal, Facultad de Química, Universidad Autónoma de Querétaro, Cerro de las Campanas S/N, C.P. 76010 Querétaro, Mexico.
  • Del Real A; Programa de Maestría en Ciencias de la Nutrición Humana, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Av. de las Ciencias S/N, C.P. 76230 Juriquilla, Querétaro, Mexico.
  • Rubio E; Centro de Física Aplicada y Tecnología Avanzada, Universidad Nacional Autónoma de México, C.P. 7600 Juriquilla, Querétaro, Mexico.
  • Jiménez-Mendoza D; Centro Universitario de Vinculación y Transferencia de Tecnología, Benemérita Universidad Autónoma de Puebla, Centro Universitario, Col. San Manuel S/N, C.P. 72540 Puebla, Mexico.
  • Rojas-Molina I; Departamento de Ingeniería Física, División de Ciencias e Ingenierías, Universidad de Guanajuato, Campus León, Lomas del Bosque 103, Col. Lomas del Campestre, C.P. 37150 León, Guanajuato, Mexico.
Nutrients ; 12(5)2020 May 15.
Article em En | MEDLINE | ID: mdl-32429103
Osteoporosis is a disease of the skeletal system characterized by low bone mass and bone weakening, which increase the risk of fracture. This disease is associated with menopause because hypoestrogenism induces the maturation and activation of osteoclasts. In addition, a low dietary intake of calcium leads to low bone mineral density and postmenopausal osteoporosis. The objectives of this work were to determine calcium bioavailability of Opuntia ficus-indica cladodes at a late maturity stage and to assess its contribution in improving bone health in an ovariectomized rat model. Two-month-old Wistar female rats (n = 35) were used and distributed in seven experimental groups: (i) control group (Crtl), (ii) sham group (SH), (iii) ovariectomized group (OVX), (iv) ovariectomized group supplemented with calcium citrate (CCa), (v) ovariectomized group supplemented with O. ficus-indica powder (NI), (vi) ovariectomized group supplemented with soluble fiber from O. ficus-indica (FS) and (vii) ovariectomized group supplemented with insoluble fiber from O. ficus-indica (FI). Our results showed that calcium in the soluble fiber of O. ficus-indica is bioavailable and contributes to improve the physical, densitometric, biomechanical and microstructural properties of bones in ovariectomized rats. These findings indicated that O. ficus-indica cladodes at a late maturity stage represent a good source of bioavailable calcium and consumption of these cladodes might be beneficial for the prevention of osteoporosis and other bone diseases.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cálcio da Dieta / Extratos Vegetais / Osteoporose Pós-Menopausa / Citrato de Cálcio / Opuntia Limite: Animals / Female / Humans Idioma: En Revista: Nutrients Ano de publicação: 2020 Tipo de documento: Article País de afiliação: México País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cálcio da Dieta / Extratos Vegetais / Osteoporose Pós-Menopausa / Citrato de Cálcio / Opuntia Limite: Animals / Female / Humans Idioma: En Revista: Nutrients Ano de publicação: 2020 Tipo de documento: Article País de afiliação: México País de publicação: Suíça