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Butyrospermum parkii butter increased the photostability and in vivo SPF of a molded sunscreen system.
Sarruf, Fernanda D; Sauce, Rafael; Candido, Thalita M; Oliveira, Camila A; Rosado, Catarina; Velasco, Maria V R; Baby, André R.
Afiliação
  • Sarruf FD; Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
  • Sauce R; Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
  • Candido TM; Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
  • Oliveira CA; Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
  • Rosado C; CBIOS - Universidade Lusófona's Research Center for Biosciences and Health Technologies, Lisbon, Portugal.
  • Velasco MVR; Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
  • Baby AR; Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
J Cosmet Dermatol ; 19(12): 3296-3301, 2020 Dec.
Article em En | MEDLINE | ID: mdl-32385930
BACKGROUND: Ultraviolet (UV) radiation exposure is related to skin and lip tumors. Therefore, the development of photoprotective lipstick formulations is of utmost importance. AIMS: Considering the biological properties of Shea butter (Butyrospermum parkii), we assessed its potential as an adjuvant in a molded lipstick sunscreen system by in vivo tests and photostability. PATIENTS/METHODS: Shea butter was used in a photoprotective lipstick formulation at two different concentrations (10.0% and 15.0% w/w) associated with ethylhexyl methoxycinnamate (EHM) and titanium dioxide. Skin compatibility was assessed in vivo. The in vivo SPF value was determined according to the current recognized method. Additionally, the photostability of EHM was determined by high-performance liquid chromatography. RESULTS: By the cutaneous compatibility, the product presented no interference with skin barrier and no adverse reactions, thus proving its safety. The in vivo SPF assay showed that the highest concentration of Shea butter increased the in vivo SPF value of the sample by 35%, demonstrating it to be a booster in photoprotective lipstick formulations. Also, Shea butter was proved to enhance the photostability of EHM, a commonly used UVB filter available in several countries. CONCLUSION: Shea butter increased the photostability and in vivo SPF of a molded lipstick sunscreen.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protetores Solares / Neoplasias Labiais Limite: Humans Idioma: En Revista: J Cosmet Dermatol Assunto da revista: DERMATOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protetores Solares / Neoplasias Labiais Limite: Humans Idioma: En Revista: J Cosmet Dermatol Assunto da revista: DERMATOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido