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Impact of Renal Transplantation and Immunosuppressive Therapy on Muscle Strength, Functional Capacity, and Quality of Life: A Longitudinal Study.
Gil, Ana Paula Pereira; Lunardi, Adriana Claudia; Santana, Fernanda Ribeiro; Bergamim, Juliana Santi Sagin Pinto; Sarmento, Laís Azevedo; Cristelli, Marina Pontello; Chiavegato, Luciana Dias.
Afiliação
  • Gil APP; Masters and Doctoral Programs in Physical Therapy, Universidade Cidade de São Paulo, São Paulo, Brazil.
  • Lunardi AC; Masters and Doctoral Programs in Physical Therapy, Universidade Cidade de São Paulo, São Paulo, Brazil; Department of Physical Therapy of School of Medicine, Universidade de São Paulo, São Paulo, Brazil.
  • Santana FR; Masters and Doctoral Programs in Physical Therapy, Universidade Cidade de São Paulo, São Paulo, Brazil.
  • Bergamim JSSP; Masters and Doctoral Programs in Physical Therapy, Universidade Cidade de São Paulo, São Paulo, Brazil; Instituto Cuiabá de Ensino e Cultura - Cuiabá, Mato Grosso, Brazil.
  • Sarmento LA; Masters and Doctoral Programs in Physical Therapy, Universidade Cidade de São Paulo, São Paulo, Brazil.
  • Cristelli MP; Hospital do Rim e Hipertensão, São Paulo, Brazil.
  • Chiavegato LD; Masters and Doctoral Programs in Physical Therapy, Universidade Cidade de São Paulo, São Paulo, Brazil; Respiratory Division, Medicine Department, Federal University of São Paulo, São Paulo, São Paulo, Brazil. Electronic address: lu_chiavegato@uol.com.br.
Transplant Proc ; 52(5): 1279-1283, 2020 Jun.
Article em En | MEDLINE | ID: mdl-32307144
Renal transplantation is the best long-term treatment option compared with maintenance dialysis in patients with chronic kidney disease. This treatment should be combined with immunosuppressive drugs to obtain positive effects; however, the adverse effects of these medications in the respiratory and peripheral muscle strength, functional capacity, and quality of life of patients remain unknown. OBJECTIVE: The objective of this study is to evaluate the respiratory and peripheral muscle strength, functional capacity, and quality of life of patients undergoing renal transplantation in the preoperative period and during the first 6 months of postoperative period. METHODS: The respiratory and peripheral muscle strength, quality of life, and functional capacity of 40 patients were evaluated from the pretransplant period to 6 months post-renal transplantation. RESULTS: Compared with the preoperative period, the patients experienced improvement of the respiratory and peripheral strength 6 months after transplant (maximal inspiratory pressure 44% and maximal expiratory pressure 28.96%, handgrip 13.81%, and lower limbs 26.95%) and also in the quality of life. CONCLUSION: We conclude that 6 months after transplant, patients showed improvement in respiratory and peripheral muscle strength and quality of life, but even with the improvement, patients presented an unsatisfactory quality of life and muscle strength, regardless of immunosuppressive therapy.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Terapia de Imunossupressão / Transplante de Rim / Insuficiência Renal Crônica / Força Muscular Tipo de estudo: Evaluation_studies / Observational_studies Aspecto: Patient_preference Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Transplant Proc Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Terapia de Imunossupressão / Transplante de Rim / Insuficiência Renal Crônica / Força Muscular Tipo de estudo: Evaluation_studies / Observational_studies Aspecto: Patient_preference Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Transplant Proc Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos