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Predictive role of Selvester QRS score in patients undergoing transcatheter aortic valve replacement.
Bignoto, Tiago Costa; Le Bihan, David; de Mattos Barretto, Rodrigo Bellio; de Oliveira Ramos, Auristela Isabel; Moreira, Dalmo Antônio Ribeiro; Simonato, Matheus; de Alvim Siqueira, Dimytri Alexandre; Pinto, Ibraim Masciarelli Francisco; Dos Santos, Tiago Senra Garcia; de Moraes Rego Sousa, Amanda Guerra; Abizaid, Alexandre.
Afiliação
  • Bignoto TC; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
  • Le Bihan D; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
  • de Mattos Barretto RB; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
  • de Oliveira Ramos AI; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
  • Moreira DAR; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
  • Simonato M; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
  • de Alvim Siqueira DA; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
  • Pinto IMF; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
  • Dos Santos TSG; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
  • de Moraes Rego Sousa AG; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
  • Abizaid A; Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
Catheter Cardiovasc Interv ; 97(1): E95-E103, 2021 01 01.
Article em En | MEDLINE | ID: mdl-32301250
INTRODUCTION: Few data exist regarding the late clinical impact of the Selvester score prediction of myocardial fibrosis after transcatheter aortic valve replacement (TAVR). This study evaluated the predictive power of the Selvester score on survival in patients with aortic stenosis (AS) undergoing TAVR. METHODS AND RESULTS: Patients with severe AS who had preoperative electrocardiograms were included. Clinical follow-up was obtained retrospectively. The primary endpoint was all-cause mortality. Secondary endpoints were cardiovascular death and major adverse cardiac events (MACEs). Two-hundred twenty-eight patients were included (mean age, 81.5 ± 7.4 years; women, 58.3%). Deceased patients had a higher mean score (4.6 ± 3.2 vs. 1.4 ± 1.3; p < .001). At a mean follow-up of 36.2 ± 21.2 months, the Selvester score was independently associated with all-cause mortality (hazard ratio [HR], 1.65; 95% confidence interval [CI], 1.48-1.84; p < .001), cardiovascular death (HR, 1.59; 95% CI, 1.38-1.74; p < .001), and MACE (HR, 1.55; 95% CI, 1.30-1.68; p < .001). After 5 years, the mortality risk was incrementally related to the Selvester score. The involvement of the inferior wall of the left ventricle was a lower mortality risk factor (HR, 0.42; 95% CI, 0.18-0.98; p = .046). For a Selvester score of 3, the area under the curve showed 0.92, 0.94, and 0.86 (p < .001), respectively, for 1, 2, and 3 years. CONCLUSIONS: Elevated Selvester scores increase the risk of poor outcomes in patients with AS undergoing TAVR. The involvement of the anterior or lateral wall presents worse prognosis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estenose da Valva Aórtica / Substituição da Valva Aórtica Transcateter Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged80 / Female / Humans Idioma: En Revista: Catheter Cardiovasc Interv Assunto da revista: CARDIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estenose da Valva Aórtica / Substituição da Valva Aórtica Transcateter Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged80 / Female / Humans Idioma: En Revista: Catheter Cardiovasc Interv Assunto da revista: CARDIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos