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Ecological and evolutionary drivers of haemoplasma infection and bacterial genotype sharing in a Neotropical bat community.
Becker, Daniel J; Speer, Kelly A; Brown, Alexis M; Fenton, M Brock; Washburne, Alex D; Altizer, Sonia; Streicker, Daniel G; Plowright, Raina K; Chizhikov, Vladimir E; Simmons, Nancy B; Volokhov, Dmitriy V.
Afiliação
  • Becker DJ; Department of Biology, Indiana University, Bloomington, IN, USA.
  • Speer KA; Center for the Ecology of Infectious Disease, University of Georgia, Athens, GA, USA.
  • Brown AM; Richard Gilder Graduate School, American Museum of Natural History, New York, NY, USA.
  • Fenton MB; Department of Invertebrate Zoology, National Museum of Natural History, Smithsonian Institution, Washington, DC, USA.
  • Washburne AD; Center for Conservation Genomics, Smithsonian Conservation Biology Institute, National Zoological Park, Washington, DC, USA.
  • Altizer S; Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY, USA.
  • Streicker DG; Department of Biology, Western University, London, ON, Canada.
  • Plowright RK; Department of Microbiology and Immunology, Montana State University, Bozeman, MT, USA.
  • Chizhikov VE; Center for the Ecology of Infectious Disease, University of Georgia, Athens, GA, USA.
  • Simmons NB; Odum School of Ecology, University of Georgia, Athens, GA, USA.
  • Volokhov DV; Odum School of Ecology, University of Georgia, Athens, GA, USA.
Mol Ecol ; 29(8): 1534-1549, 2020 04.
Article em En | MEDLINE | ID: mdl-32243630
Most emerging pathogens can infect multiple species, underlining the importance of understanding the ecological and evolutionary factors that allow some hosts to harbour greater infection prevalence and share pathogens with other species. However, our understanding of pathogen jumps is based primarily around viruses, despite bacteria accounting for the greatest proportion of zoonoses. Because bacterial pathogens in bats (order Chiroptera) can have conservation and human health consequences, studies that examine the ecological and evolutionary drivers of bacterial prevalence and barriers to pathogen sharing are crucially needed. Here were studied haemotropic Mycoplasma spp. (i.e., haemoplasmas) across a species-rich bat community in Belize over two years. Across 469 bats spanning 33 species, half of individuals and two-thirds of species were haemoplasma positive. Infection prevalence was higher for males and for species with larger body mass and colony sizes. Haemoplasmas displayed high genetic diversity (21 novel genotypes) and strong host specificity. Evolutionary patterns supported codivergence of bats and bacterial genotypes alongside phylogenetically constrained host shifts. Bat species centrality to the network of shared haemoplasma genotypes was phylogenetically clustered and unrelated to prevalence, further suggesting rare-but detectable-bacterial sharing between species. Our study highlights the importance of using fine phylogenetic scales when assessing host specificity and suggests phylogenetic similarity may play a key role in host shifts not only for viruses but also for bacteria. Such work more broadly contributes to increasing efforts to understand cross-species transmission and the epidemiological consequences of bacterial pathogens.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quirópteros Tipo de estudo: Risk_factors_studies Limite: Animals / Humans / Male País/Região como assunto: America central / Belice / Caribe ingles Idioma: En Revista: Mol Ecol Assunto da revista: BIOLOGIA MOLECULAR / SAUDE AMBIENTAL Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quirópteros Tipo de estudo: Risk_factors_studies Limite: Animals / Humans / Male País/Região como assunto: America central / Belice / Caribe ingles Idioma: En Revista: Mol Ecol Assunto da revista: BIOLOGIA MOLECULAR / SAUDE AMBIENTAL Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido