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The potential role of dietary advanced glycation endproducts in the development of chronic non-infectious diseases: a narrative review.
Garay-Sevilla, M E; Beeri, M S; de la Maza, M P; Rojas, A; Salazar-Villanea, S; Uribarri, J.
Afiliação
  • Garay-Sevilla ME; Medical Science Department, University of Guanajuato, Guanajuato, Mexico.
  • Beeri MS; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • de la Maza MP; The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, Israel.
  • Rojas A; Institute of Nutrition and Food Technology Dr. Fernando Monckeberg Barros, University of Chile, Santiago, Chile.
  • Salazar-Villanea S; Biomedical Research Laboratories, Faculty of Medicine, Catholic University of Maule, Talca, Chile.
  • Uribarri J; Department of Animal Science, Universidad de Costa Rica, San Pedro Montes de Oca, San José, Costa Rica.
Nutr Res Rev ; 33(2): 298-311, 2020 12.
Article em En | MEDLINE | ID: mdl-32238213
Increasing clinical and experimental evidence accumulated during the past few decades supports an important role for dietary advanced glycation endproducts (AGE) in the pathogenesis of many chronic non-infectious diseases, such as type 2 diabetes, CVD and others, that are reaching epidemic proportions in the Western world. Although AGE are compounds widely recognised as generated in excess in the body in diabetic patients, the potential importance of exogenous AGE, mostly of dietary origin, has been largely ignored in the general nutrition audience. In the present review we aim to describe dietary AGE, their mechanisms of formation and absorption into the body as well as their main mechanisms of action. We will present in detail current evidence of their potential role in the development of several chronic non-infectious clinical conditions, some general suggestions on how to restrict them in the diet and evidence regarding the potential benefits of lowering their consumption.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Finais de Glicação Avançada / Dieta / Doenças não Transmissíveis Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Nutr Res Rev Assunto da revista: CIENCIAS DA NUTRICAO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Finais de Glicação Avançada / Dieta / Doenças não Transmissíveis Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Nutr Res Rev Assunto da revista: CIENCIAS DA NUTRICAO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido