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Impairment of myocardial functions and arterial stiffness in patients with lichen planus.
Baykal Selcuk, Leyla; Sahin, Mursel; Arica, Deniz Aksu; Orem, Asim; Karaca Ural, Zeynep; Yayli, Savas.
Afiliação
  • Baykal Selcuk L; Department of Dermatology, Karadeniz Technical University, School of Medicine, Trabzon, Turkey. Electronic address: dr.leylabaykal@gmail.com.
  • Sahin M; Department of Dermatology, Karadeniz Technical University, School of Medicine, Trabzon, Turkey.
  • Arica DA; Department of Dermatology, Karadeniz Technical University, School of Medicine, Trabzon, Turkey.
  • Orem A; Department of Biochemistry, Karadeniz Technical University, School of Medicine, Trabzon, Turkey.
  • Karaca Ural Z; Department of Dermatology, Karadeniz Technical University, School of Medicine, Trabzon, Turkey.
  • Yayli S; Department of Dermatology, Karadeniz Technical University, School of Medicine, Trabzon, Turkey.
An Bras Dermatol ; 95(2): 180-186, 2020.
Article em En | MEDLINE | ID: mdl-32146010
BACKGROUND: Lichen planus is a chronic inflammatory mucocutaneous disease. Recent studies have suggested that it is associated with an increased risk of cardiovascular comorbidities. OBJECTIVE: The purpose of this study was to assess and compare arterial stiffness and cardiovascular hemodynamics in patients with lichen planus and a healthy control group. METHODS: Fifty-five patients with lichen planus and 42 healthy controls were enrolled. All patients underwent echocardiographic examination, and arterial stiffness was measured using applanation tonometry. RESULTS: No statistically significant difference was determined between the patient and control groups in terms of arterial stiffness, but stiffness was markedly higher in patients with erosive lichen planus compared to the control group and other patients (p=0.006, and p=0.023, respectively). Moderate positive correlation was determined between duration of disease and arterial stiffness. Impairment of systolic and diastolic functions was also determined in patients with lichen planus compared to the control group (p<0.001, and p=0.005, respectively). STUDY LIMITATIONS: Relatively low number of patients. CONCLUSION: The positive correlation observed between duration of disease and arterial stiffness in patients with lichen planus suggests that these patients should be followed-up in terms of cardiovascular risk in the presence of resistant and long-term disease, particularly in case of erosive lichen planus.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Rigidez Vascular / Hemodinâmica / Líquen Plano Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: An Bras Dermatol Ano de publicação: 2020 Tipo de documento: Article País de publicação: Espanha
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Rigidez Vascular / Hemodinâmica / Líquen Plano Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: An Bras Dermatol Ano de publicação: 2020 Tipo de documento: Article País de publicação: Espanha