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Evaluation of effects of Poincianella bracteosa (Tul.) L.P. Queiroz leaves in Allium cepa and Mus musculus.
Pereira, M L; Monteiro, C N; Siqueira, Cfn; Ribeiro, M S; Lopes, A P; Sousa, Rms; Oliveira, Mda; Júnior, Jsc; Martins, F A; Almeida, P M.
Afiliação
  • Pereira ML; Center of Health Sciences (CCS), State University of Piauí (UESPI/FACIME), Department of Genetics, Laboratory of Genetics. Rua Olavo Bilac , 2335, 64.049-570 Teresina PI, Brazil.
  • Monteiro CN; Center of Natural Sciences (CCN), State University of Piauí, Laboratory of Genetics. Rua João Cabral , 2231, 64.002-150 Teresina PI, Brazil.
  • Siqueira C; Center of Health Sciences (CCS), State University of Piauí (UESPI/FACIME), Department of Genetics, Laboratory of Genetics. Rua Olavo Bilac , 2335, 64.049-570 Teresina PI, Brazil.
  • Ribeiro MS; Center of Natural Sciences (CCN), State University of Piauí, Laboratory of Genetics. Rua João Cabral , 2231, 64.002-150 Teresina PI, Brazil.
  • Lopes AP; Center of Health Sciences (CCS), State University of Piauí (UESPI/FACIME), Department of Genetics, Laboratory of Genetics. Rua Olavo Bilac , 2335, 64.049-570 Teresina PI, Brazil.
  • Sousa R; Center of Natural Sciences (CCN), State University of Piauí, Laboratory of Genetics. Rua João Cabral , 2231, 64.002-150 Teresina PI, Brazil.
  • Oliveira M; Center of Natural Sciences (CCN), Federal Institute of Piauí, Laboratory of Organic Chemistry and Natural Products , Teresina PI, Brazil.
  • Júnior J; Center of Natural Sciences (CCN), Federal Institute of Piauí, Laboratory of Organic Chemistry and Natural Products , Teresina PI, Brazil.
  • Martins FA; Center of Natural Sciences (CCN), State University of Piauí, Laboratory of Genetics. Rua João Cabral , 2231, 64.002-150 Teresina PI, Brazil.
  • Almeida PM; Center of Health Sciences (CCS), State University of Piauí (UESPI/FACIME), Department of Genetics, Laboratory of Genetics. Rua Olavo Bilac , 2335, 64.049-570 Teresina PI, Brazil.
Biotech Histochem ; 95(6): 464-473, 2020 Aug.
Article em En | MEDLINE | ID: mdl-32037888
POINCIANELLA BRACTEOSA: (Tul.) L.P. Queiroz. (Fabaceae) traditionally is used in Brazilian medicine to treat catarrhal infections, diarrhea, hepatitis and anemia. We investigated the phytochemical profile, and mutagenicity and anti-mutagenicity of aqueous extracts of leaves of P. bracteosa in A. cepa cells and in mice. We investigated four concentrations of extract for the A. cepa bioassay and three doses of extract for administration to mice. For the A. cepa assay, we analyzed 5,000 meristematic cells to determine the mitotic index, mean number of chromosome alterations and percentage of damage reduction. For each animal assay, 2,000 normochromatic erythrocytes were evaluated per mouse to determine the number of micronuclei and the protective effect of the extract. Phytochemical analysis of the extract revealed reducing sugars, tannins and alkaloids, which likely did not interfere with the cell cycle of A. cepa or cause damage to the DNA of A. cepa or mice. The extract exhibited a protective effect in both organisms.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Allium / Extratos Vegetais / Folhas de Planta / Cebolas Limite: Animals Idioma: En Revista: Biotech Histochem Assunto da revista: HISTOCITOQUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Allium / Extratos Vegetais / Folhas de Planta / Cebolas Limite: Animals Idioma: En Revista: Biotech Histochem Assunto da revista: HISTOCITOQUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido