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ß2 adrenergic interaction and cardiac autonomic function: effects of aerobic training in overweight/obese individuals.
Rodrigues, Jhennyfer Aline Lima; Ferrari, Gustavo Duarte; Trapé, Átila Alexandre; de Moraes, Vitor Nolasco; Gonçalves, Thiago Correa Porto; Tavares, Simone Sakagute; Tjønna, Arnt Erik; de Souza, Hugo Celso Dutra; Júnior, Carlos Roberto Bueno.
Afiliação
  • Rodrigues JAL; School of Nursing of Ribeirão Preto, University of São Paulo (USP), Bandeirantes Avenue 3900, Ribeirão Preto, SP, 14040-907, Brazil. jhennyrodrigues@usp.br.
  • Ferrari GD; Laboratory of Physiology and Metabolism, School of Physical Education and Sport of Ribeirão Preto, University of São Paulo, Bandeirantes AvenueCEP 14.040-907, Ribeirão Preto, SP, 3900, Brazil. jhennyrodrigues@usp.br.
  • Trapé ÁA; Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Bandeirantes Avenue 3900, Ribeirão Preto, SP, 14040-903, Brazil.
  • de Moraes VN; School of Nursing of Ribeirão Preto, University of São Paulo (USP), Bandeirantes Avenue 3900, Ribeirão Preto, SP, 14040-907, Brazil.
  • Gonçalves TCP; Ribeirão Preto Medical School, Department of Medical Clinic, University of São Paulo (USP), Bandeirantes Avenue 3900, Ribeirão Preto, SP, 14040-907, Brazil.
  • Tavares SS; Ribeirão Preto Medical School, Department of Medical Clinic, University of São Paulo (USP), Bandeirantes Avenue 3900, Ribeirão Preto, SP, 14040-907, Brazil.
  • Tjønna AE; Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Bandeirantes Avenue 3900, Ribeirão Preto, SP, 14040-903, Brazil.
  • de Souza HCD; K.G. Jebsen Center of Exercise in Medicine at Department of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
  • Júnior CRB; Ribeirão Preto Medical School, Exercise Physiology Laboratory, Department of Health Science, University of São Paulo (USP), Bandeirantes Avenue, 3900Vila Monte Alegre, Ribeirão Preto, SP, 14049-900, Brazil.
Eur J Appl Physiol ; 120(3): 613-624, 2020 Mar.
Article em En | MEDLINE | ID: mdl-31915906
PURPOSE: To verify the influence of different volumes and intensities of aerobic exercise on cardiac autonomic function (CAF) through heart rate variability (HRV) analysis as well the influence of ß2 adrenergic receptor (ADRB2) variants in overweight/obese individuals. METHODS: 70 physically inactive adults were randomly allocated into the following 16-week training: 1-high-intensity interval training (HIIT) (n = 25, 1 × 4 min bout at 85-95%HR peak, 3×/week), 4-HIIT (n = 26, 4 × 4 min bouts at 85-95%HR peak, interspersed with 3 min of recovery at 50-70%HR peak, 3×/week), and moderate continuous training (MCT) (n = 19, 30 min at 60-70%HR peak, 5×/week). Before and after the exercise training, anthropometric, BP, cardiorespiratory fitness, and HRV measures were evaluated. R-R intervals recorded for 10 min in a supine position at pre- and post-intervention were used to analyze HRV in the plot-Poincare indexes (SD1, SD2), and frequency-domain (LF, HF, LF/HF). Full blood samples were used for genotyping. RESULTS: 4-HIIT and MCT showed positive outcomes for almost all variables while 1-HIIT had a positive influence only on SBP and SD2 index. No associations were observed between isolated ADRB2 variants and changes in HRV. In the analysis of the interaction genotypes, all groups responded positively for the SD1 index of HRV and only the H1 (GG and CC) and H2 (GG and CG + GG) groups presented increases in the RMSSD index. Furthermore, there was an increase in the LF index only in the H3 (CC and AA + AG) and H4 (AA + AG and CG + GG) groups. CONCLUSIONS: ADRB2 variants and aerobic exercise training are important interacting variables to improve autonomic function and other health variables outcomes in overweight or obese individuals.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Nervoso Autônomo / Receptores Adrenérgicos beta 2 / Treinamento Intervalado de Alta Intensidade / Frequência Cardíaca / Obesidade Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Appl Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha
Texto completo
Adicionar na Minha BVS
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Nervoso Autônomo / Receptores Adrenérgicos beta 2 / Treinamento Intervalado de Alta Intensidade / Frequência Cardíaca / Obesidade Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Appl Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha