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Epidemiological analysis of 1404 patients with intracranial aneurysm followed in a single Brazilian institution.
Júnior, Jefferson Rosi; Telles, João Paulo Mota; da Silva, Saul Almeida; Iglesio, Ricardo Ferrareto; Brigido, Mauricio Mandel; Pereira Caldas, José Guilherme Mendes; Teixeira, Manoel Jacobsen; Figueiredo, Eberval Gadelha.
Afiliação
  • Júnior JR; Division of Neurological Surgery, Hospital das Clinicas HCFMUSP, University of Sao Paulo.
  • Telles JPM; School of Medicine, University of Sao Paulo.
  • da Silva SA; Division of Neurological Surgery, Hospital das Clinicas HCFMUSP, University of Sao Paulo.
  • Iglesio RF; Division of Neurological Surgery, Hospital das Clinicas HCFMUSP, University of Sao Paulo.
  • Brigido MM; Division of Neurological Surgery, Hospital das Clinicas HCFMUSP, University of Sao Paulo.
  • Pereira Caldas JGM; Service of Interventional Radiology, Radiology Institute, Hospital das Clinicas HCFMUSP, University of Sao Paulo, Sao Paulo, Brazil.
  • Teixeira MJ; Division of Neurological Surgery, Hospital das Clinicas HCFMUSP, University of Sao Paulo.
  • Figueiredo EG; Division of Neurological Surgery, Hospital das Clinicas HCFMUSP, University of Sao Paulo.
Surg Neurol Int ; 10: 249, 2019.
Article em En | MEDLINE | ID: mdl-31893150
BACKGROUND: We sought to evaluate the epidemiology of intracranial aneurysms in relation to location, gender, age, presence of multiple aneurysms, and comorbidities in the Brazilian population. METHODS: We performed a prospective analysis of a cohort of 1404 patients diagnosed with intracranial aneurysm admitted to the Hospital das Clinicas of the University of Sao Paulo, a referral hospital for the treatment of cerebrovascular diseases in Brazil. Patients admitted between September 2009 and September 2018 with radiological diagnosis of intracranial aneurysm were included in the study. RESULTS: A total of 2251 aneurysms were diagnosed. Females accounted for 1090 aneurysms (77.6%) and the mean age at diagnosis was 54.9 years (ranging 15-88). The most common location was middle cerebral artery (MCA) with 593 aneurysms (26.3%) followed by anterior cerebral artery (ACA) with 417 aneurysms (18.5%) and internal carotid artery in the posterior communicating segment with 405 aneurysms (18.0%). Males had higher rates of ACA aneurysms (29.7%) while females had higher rates of MCA aneurysms (26.1%). Sorting by size, 492 aneurysms were <5 mm (21.8%), 1524 measured 5-10 mm (67.7%), 119 size 11-24 mm (5.3%), and 116 were >24 mm (5.2%). The occurrence of multiple aneurysms was associated with female gender (P < 0.001) and smoking (P < 0.001), but not with hypertension (P = 0.121). CONCLUSION: In this population, the occurrence of intracranial aneurysm is related to several factors, including gender, age, smoking, and hypertension. Our study brought to light important characteristics of a large number of Brazilian patients regarding epidemiology, location, size, and multiplicity of intracranial aneurysms.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies País/Região como assunto: America do sul / Brasil Idioma: En Revista: Surg Neurol Int Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies País/Região como assunto: America do sul / Brasil Idioma: En Revista: Surg Neurol Int Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos