Effects of the relative positioning between the disc-fovea angle and localized optic disc defects on the 10-2 visual field results in glaucoma.
Ophthalmol Glaucoma
; 1(3): 175-181, 2018.
Article
em En
| MEDLINE
| ID: mdl-31737863
PURPOSE: To investigate the effects of the foveal position relative to the optic disc on the 10-2 visual field (VF) results of glaucoma patients with localized inferotemporal neuroretinal rim defects (ITD). DESIGN: Cross-sectional study. PARTICIPANTS: Fifty-seven eyes of 35 open-angle glaucoma (OAG) patients were included and divided into two groups based upon the presence (18 eyes) or not (39 eyes) of ITD. METHODS: Three different parameters obtained from a spectral domain optic coherence tomography (sdOCT) [disc-fovea angle (DFA), fovea vertical deviation (FVD) from midline, and the angular difference between the ITD border and the DFA (DAD)] were tested for their relationship with four 10-2 VF sectors: superior hemifield, superior edge, nasal edge, and superonasal arcuate. These relationships were tested with regression analyses with linear mixed effects models and random intercepts. MAIN OUTCOME MEASURES: Influences of DFA, FVD, and DAD on 10-2 VF sectors. RESULTS: Mean (±SD) values of DFA, FVD, and DAD were respectively: -5.05° ± 4.40°, -1346.6 um ± 1609.0 um, and 43.30° ± 17.33°. After adjustment for multiple comparisons, both FVD and DAD, but not DFA, were significantly associated with the severity of defects on the predefined VF sectors. Larger DAD values (third tertile: 54°-77°) showed higher coefficient estimate for the nasal edge sector sensitivities. CONCLUSIONS: The vertical foveal location and its position relative to the ITD was associated with loss of sensitivity at 10-2 VF locations in the superior hemifield. This association was significant but weak and was not seen using other conventional parameters that describe foveal position relative to the optic disc on sdOCT.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Disco Óptico
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Células Ganglionares da Retina
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Glaucoma de Ângulo Aberto
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Tomografia de Coerência Óptica
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Fóvea Central
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Pressão Intraocular
Tipo de estudo:
Clinical_trials
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Diagnostic_studies
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Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Ophthalmol Glaucoma
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Estados Unidos