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Steroids in pediatric acute respiratory distress syndrome.
Monteverde-Fernández, Nicolás; Cristiani, Federico; McArthur, Jenniffer; González-Dambrauskas, Sebastián.
Afiliação
  • Monteverde-Fernández N; Red Colaborativa Pediátrica de Latinoamérica (LARed Network), Uruguay.
  • Cristiani F; Medica Uruguaya Corporación Asistencia Médica (MUCAM). Cuidados Intensivos Neonatales y Pediatricos (CINP), Uruguay.
  • McArthur J; Department of Anesthesiology, Centro Hospitalario Pereira Rossell, Cátedra de Anestesiología, Universidad de la República, Montevideo, Uruguay.
  • González-Dambrauskas S; Division of Critical Care, Department of Pediatrics, St. Jude's Children's Research Hospital, Memphis, TN, USA.
Ann Transl Med ; 7(19): 508, 2019 Oct.
Article em En | MEDLINE | ID: mdl-31728361
Acute respiratory distress syndrome (ARDS) is a complex entity with high potential for harm and healthcare resource utilization. Despite multiple clinical advances in its ventilatory management, ARDS continues to be one of the most challenging disease processes for intensivists. It continues to lack a direct, proven and desperately needed effective therapeutic intervention. Given their biologic rationale, corticosteroids have been widely used by clinicians and considered useful by many in the management of ARDS since its first description. Adult data is abundant, yet contradictory. Controversy remains regarding the routine use of corticosteroids in ARDS. Therefore, widespread evidence-based recommendations for this heterogeneous disease process have not been made. In this article, our aim was to provide a summary of available evidence for the role of steroids in the treatment of ARDS, while giving special focus on pediatric ARDS (PARDS).
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Ann Transl Med Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Uruguai País de publicação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Ann Transl Med Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Uruguai País de publicação: China