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Attenuation of secondary damage and Aß deposits in the ipsilateral thalamus of dMCAO rats through reduction of cathepsin B by bis(propyl)-cognitin, a multifunctional dimer.
Zuo, Xialin; Hu, Shengquan; Tang, Yanyan; Zhan, Lixuan; Sun, Weiwen; Zheng, Jianhua; Han, Yifan; Xu, En.
Afiliação
  • Zuo X; Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province, Ministry of Education of China, 250 Changgang Dong RD, Guangzhou, 510260, China; Department of Appl
  • Hu S; Department of Applied Biology and Chemical Technology, Institute of Modern Chinese Medicine, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
  • Tang Y; Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province, Ministry of Education of China, 250 Changgang Dong RD, Guangzhou, 510260, China.
  • Zhan L; Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province, Ministry of Education of China, 250 Changgang Dong RD, Guangzhou, 510260, China.
  • Sun W; Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province, Ministry of Education of China, 250 Changgang Dong RD, Guangzhou, 510260, China.
  • Zheng J; Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province, Ministry of Education of China, 250 Changgang Dong RD, Guangzhou, 510260, China.
  • Han Y; Department of Applied Biology and Chemical Technology, Institute of Modern Chinese Medicine, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China. Electronic address: bcyfhan@polyu.edu.hk.
  • Xu E; Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province, Ministry of Education of China, 250 Changgang Dong RD, Guangzhou, 510260, China. Electronic address
Neuropharmacology ; 162: 107786, 2020 01 01.
Article em En | MEDLINE | ID: mdl-31726074
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tacrina / Catepsina B / Peptídeos beta-Amiloides / Fármacos Neuroprotetores / Núcleos Ventrais do Tálamo / Infarto da Artéria Cerebral Média / Antagonistas de Receptores de GABA-A Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neuropharmacology Ano de publicação: 2020 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tacrina / Catepsina B / Peptídeos beta-Amiloides / Fármacos Neuroprotetores / Núcleos Ventrais do Tálamo / Infarto da Artéria Cerebral Média / Antagonistas de Receptores de GABA-A Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neuropharmacology Ano de publicação: 2020 Tipo de documento: Article País de publicação: Reino Unido