Your browser doesn't support javascript.
loading
Mandatory notifications of type 1 diabetes incident cases in Chilean children, 2006 to 2014: A population-based study.
Garfias, Carolina P; Borzutzky, Arturo; Ugarte, María F; García, Hernán J; Phingsthorn, Martin; García, Hernán G.
Afiliação
  • Garfias CP; Division of Pediatrics, Pontificia Universidad Católica de Chile School of Medicine, Santiago, Chile.
  • Borzutzky A; Pediatric Endocrinology Unit, Universidad de Los Andes, Santiago, Chile.
  • Ugarte MF; Division of Pediatrics, Pontificia Universidad Católica de Chile School of Medicine, Santiago, Chile.
  • García HJ; Millennium Institute on Immunology and Immunotherapy, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Phingsthorn M; Pediatric Endocrinology Unit, Universidad de Los Andes, Santiago, Chile.
  • García HG; School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pediatr Diabetes ; 21(1): 48-52, 2020 02.
Article em En | MEDLINE | ID: mdl-31628775
Type 1 diabetes mellitus (T1D) incidence in children varies across regions and countries, showing a continuous rise globally. Chile has mandatory T1D notification and guaranteed access to diagnosis and treatment since 2005, providing a strong model to evaluate T1D epidemiology. OBJECTIVE: To determine T1D incidence in Chilean population under 20 years between 2006 and 2014. METHODS: We reviewed mandatory notifications of T1D in Chile's public health system. RESULTS: A total of 4153 T1D cases in population under 20 years were notified from 2006 to 2014. Median age was 14 years and 51% were male. The average annual T1D incidence was 12 per 100 000 population, with an increase from 10.2 in 2006 to 13.8 in 2014 (ß 0.5 95% confidence interval [CI] 0.4-0.7, P < .001). A significantly increasing linear trend of T1D incidence was observed in groups of 0 to 4 years (ß 0.33, 95% CI 0.06-0.59, P = .02), 5 to 9 years (ß 0.68 95% CI 0.27-1.10, P = .006), and 10 to 14 (ß 0.94, 95% CI 0.67-1.20, P < .001), but increase was less pronounced in the oldest children aged between 15 and 19 years (ß 0.22, 95% CI -0.03 to 0.44, P = .052). The lowest regional T1D incidence was observed in the Araucanía region, which has the highest rate of indigenous population. CONCLUSION: Incidence rates of T1D in Chile, evaluated through a mandatory notification program, are rapidly increasing in children and adolescents. If increasing trends persist, Chile will reach T1D incidence rates of Western developed countries in the next decade.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 1 Tipo de estudo: Diagnostic_studies / Incidence_studies / Observational_studies / Prognostic_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Newborn País/Região como assunto: America do sul / Chile Idioma: En Revista: Pediatr Diabetes Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Chile País de publicação: Dinamarca
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 1 Tipo de estudo: Diagnostic_studies / Incidence_studies / Observational_studies / Prognostic_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Newborn País/Região como assunto: America do sul / Chile Idioma: En Revista: Pediatr Diabetes Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Chile País de publicação: Dinamarca