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Psychotic and affective symptoms of early-onset bipolar disorder: an observational study of patients in first manic episode.
Fu-I, Lee; Gurgel, Wagner de S; Caetano, Sheila C; Machado-Vieira, Rodrigo; Wang, Yuan P.
Afiliação
  • Fu-I L; Departamento de Psiquiatria, Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brazil.
  • Gurgel WS; Departamento de Psiquiatria, Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brazil.
  • Caetano SC; Departamento de Psiquiatria, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
  • Machado-Vieira R; University of Texas Health Science Center, Houston, TX, USA.
  • Wang YP; Departamento de Psiquiatria, Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brazil.
Braz J Psychiatry ; 42(2): 168-174, 2020 Apr.
Article em En | MEDLINE | ID: mdl-31576937
OBJECTIVE: Presence of psychotic symptoms seems to be a commonplace in early-onset bipolar disorder (BD). However, few studies have examined their occurrence in adolescent-onset BD. We sought to investigate the frequency of affective and psychotic symptoms observed during the first manic episode in adolescents. METHODS: Forty-nine adolescents with bipolar I disorder (DSM-IV criteria) were admitted to a psychiatric hospital during their first acute manic episode. Assessment for current psychiatric diagnosis was performed by direct clinical interview and the DSM-IV version of the Diagnostic Interview for Children and Adolescents (DICA). RESULTS: Teenage inpatients with BD consistently exhibited typical manic features, such as euphoria, grandiosity, and psychomotor agitation. In addition, disorganization and psychotic symptoms were present in 82 and 55% of the total sample, respectively. There was no significant difference in symptoms between early- and late-adolescent subgroups. Remarkably, most patients (76%) reported previous depressive episode(s); of these, 47% had prominent psychotic features in the prior depressive period. CONCLUSION: These findings suggest that disorganization and psychotic symptoms during the first manic episode are salient features in adolescent-onset BD, and that psychotic depression frequently may precede psychotic mania. Nevertheless, differential diagnosis with schizophrenia should be routinely ruled out in cases of early-onset first psychotic episode.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Transtorno Bipolar / Sintomas Afetivos Tipo de estudo: Diagnostic_studies / Observational_studies / Qualitative_research Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Braz J Psychiatry Assunto da revista: PSIQUIATRIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Transtorno Bipolar / Sintomas Afetivos Tipo de estudo: Diagnostic_studies / Observational_studies / Qualitative_research Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Braz J Psychiatry Assunto da revista: PSIQUIATRIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil