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Effectiveness of the mass use of deltamethrin-impregnated dog collars for preventing transmission of canine leishmaniasis by Lutzomyia spp.: A cluster randomized controlled trial.
Silva, Sara Clemente Paulino Ferreira E; Gomes, Laiza Bonela; Carvalho, Paloma Carla Fonte Boa; Santos, Aline Gabriele Ribeiro Cerqueira; Borges, Luiz Felipe Nunes Menezes; Oliveira, Camila Stefanie Fonseca; Morais, Maria Helena Franco; Pereira, Pedro Lúcio Lithg; Amaral Haddad, João Paulo; Soares, Danielle Ferreira de Magalhães.
Afiliação
  • Silva SCPFE; Departamento de Medicina Veterinária Preventiva, Escola de Medicina Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. Electronic address: scpfsilva@gmail.com.
  • Gomes LB; Departamento de Medicina Veterinária Preventiva, Escola de Medicina Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • Carvalho PCFB; Departamento de Medicina Veterinária Preventiva, Escola de Medicina Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • Santos AGRC; Departamento de Medicina Veterinária Preventiva, Escola de Medicina Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • Borges LFNM; Serviço de Controle de Zoonoses, Prefeitura de Juatuba, Juatuba, MG, Brazil.
  • Oliveira CSF; Departamento de Medicina Veterinária Preventiva, Escola de Medicina Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • Morais MHF; Secretaria Municipal de Saúde, Prefeitura de Belo Horizonte, Belo Horizonte, MG, Brazil.
  • Pereira PLL; Departamento de Medicina Veterinária Preventiva, Escola de Medicina Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • Amaral Haddad JP; Departamento de Medicina Veterinária Preventiva, Escola de Medicina Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • Soares DFM; Departamento de Medicina Veterinária Preventiva, Escola de Medicina Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Prev Vet Med ; 171: 104770, 2019 Nov 01.
Article em En | MEDLINE | ID: mdl-31536935
Visceral leishmaniasis (VL) is a zoonosis that greatly impacts public health, especially in developing countries. The effectiveness of deltamethrin-impregnated dog collars for preventing transmission of canine leishmaniasis (CanL) by the sand fly Lutzomyia spp. in countries with high incidence of the disease, such as Brazil, remains unknown. A cluster randomized controlled trial was carried out to evaluate the effectiveness of these collars in preventing infection of dogs with Leishmania infantum. Two areas were selected in a municipality endemic for VL in Brazil: an experimental area (EA) and a control area (CA). In both areas, blood samples were collected from dogs for detection of CanL. Seronegative dogs from the EA received collars impregnated with deltamethrin 4%. After six months, the dogs were retested for CanL and the incidence of the disease, the relative risk, and the effectiveness of collaring determined. In the baseline survey, 1020 dogs from the EA and 589 from the CA were examined. The prevalence calculated for EA was 4.41% (CI95% 3.27-5.91), and 7.13% (CI95% 5.25-9.59) for CA. In the second evaluation, 454 dogs from the EA and 292 from the CA were examined. The person-time incidence calculated for EA was 3.51% (CI95% 1.30-7.48), and for CA was 11.81% (CI95% 7.03-18.23). The difference between the calculated incidences was statistically significant (p = 0.009). The relative risk was 0.2972 (CI95% 0.1204-0.7339; p = 0.009), and the efficacy of the proposed measure was estimated in 70.27%. This report evaluated the effectiveness of the mass use of deltamethrin-impregnated dog collars in areas of transmission of VL by Lutzomyia spp. Collaring was able to protect dogs and may represent an effective strategy that could be implemented to control infection in both dogs and humans in Brazil and perhaps other countries where Lutzomyia spp. is the main vector of the disease.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psychodidae / Piretrinas / Doenças do Cão / Inseticidas / Leishmaniose Visceral / Nitrilas Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Pregnancy País/Região como assunto: America do sul / Brasil Idioma: En Revista: Prev Vet Med Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psychodidae / Piretrinas / Doenças do Cão / Inseticidas / Leishmaniose Visceral / Nitrilas Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Pregnancy País/Região como assunto: America do sul / Brasil Idioma: En Revista: Prev Vet Med Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda