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Comorbidities and polypharmacy among HIV-positive patients aged 50 years and over: a case-control study.
Mata-Marín, José Antonio; Martínez-Osio, Moisés Hermilo; Arroyo-Anduiza, Carla I; Berrospe-Silva, María de Los Ángeles; Chaparro-Sánchez, Alberto; Cruz-Grajales, Itzel; Cruz-Herrera, Javier Enrique; Uribe-Noguez, Luis Antonio; Gaytán-Martínez, Jesus E; Jerónimo-Morales, Medardo.
Afiliação
  • Mata-Marín JA; Infectious Diseases Department, Instituto Mexicano del Seguro Social, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Seris y Jacarandas s/n, colonia la raza, Del Azcapotzalco, PO. 02990, Mexico City, Mexico. jamatamarin@gmail.com.
  • Martínez-Osio MH; Internal Medicine Department, Hospital General, "La Raza" National Medical Center, IMSS, Mexico City, Mexico.
  • Arroyo-Anduiza CI; Clinical Pathology Department, Banco Central de Sangre, Hospital de Especialidades, "La Raza" National Medical Center, IMSS, Mexico City, Mexico.
  • Berrospe-Silva MLÁ; Infectious Diseases Department, Instituto Mexicano del Seguro Social, Unidad de Infectología "Juan I. Menchaca", Ext HGR 45, IMSS, Guadalajara, Jalisco, Mexico.
  • Chaparro-Sánchez A; Infectious Diseases Department, Instituto Mexicano del Seguro Social, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Seris y Jacarandas s/n, colonia la raza, Del Azcapotzalco, PO. 02990, Mexico City, Mexico.
  • Cruz-Grajales I; Internal Medicine Department, Hospital General, "La Raza" National Medical Center, IMSS, Mexico City, Mexico.
  • Cruz-Herrera JE; Internal Medicine Department, Hospital HGZ-# 3, Querétaro, Mexico.
  • Uribe-Noguez LA; Infectious Diseases Department, Instituto Mexicano del Seguro Social, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Seris y Jacarandas s/n, colonia la raza, Del Azcapotzalco, PO. 02990, Mexico City, Mexico.
  • Gaytán-Martínez JE; Infectious Diseases Department, Instituto Mexicano del Seguro Social, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Seris y Jacarandas s/n, colonia la raza, Del Azcapotzalco, PO. 02990, Mexico City, Mexico.
  • Jerónimo-Morales M; Internal Medicine Department, Hospital General, "La Raza" National Medical Center, IMSS, Mexico City, Mexico.
BMC Res Notes ; 12(1): 556, 2019 Sep 03.
Article em En | MEDLINE | ID: mdl-31481133
OBJECTIVE: This study was to determine and compare the prevalences of polypharmacy and comorbidities in patients aged 50 years or older with those patients younger than 50 years in a Mexican population. RESULTS: One hundred and twenty-five patients were enrolled, 60 (48%) were aged 50 years or older. The median CD4+ cell counts were 509 cells/µL (interquartile range [IQR]: 324-730) for the older patients and 384 cells/µL (IQR: 262-562) (P = 0.021) for the younger patients. Viral suppression were significantly higher in the older group: 80% vs. 63% (P = 0.037). The number of comorbidities was significantly higher in the older group, with a median of 2 (IQR: 2-3) vs. 1 (IQR: 0-1) (P ≤ 0.001). After adjustment of the logistic regression model in the older group, the following comorbidities differed between the age groups: systemic arterial hypertension (odds ratio [OR]: 15.75; 95% confidence interval [CI] 3.49-71.05; P = < 0.001), diabetes mellitus (OR: 14.36; 95% CI 1.79-115.07; P = 0.001), osteoarthritis (OR: 10.33; 95% CI 2.88-37.05; P = < 0.001), hyperlipidemia (OR: 2.78; 95% CI 1.22-6.34; P = 0.001), and polypharmacy (OR: 6.58; 95% CI 3.01-14.39; P = 0.001).
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comorbidade / Soropositividade para HIV / Polimedicação Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Humans / Middle aged Idioma: En Revista: BMC Res Notes Ano de publicação: 2019 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comorbidade / Soropositividade para HIV / Polimedicação Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Humans / Middle aged Idioma: En Revista: BMC Res Notes Ano de publicação: 2019 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido