Your browser doesn't support javascript.
loading
Dental alterations on panoramic radiographs of patients with osteogenesis imperfecta in relation to clinical diagnosis, severity, and bisphosphonate regimen aspects: a STROBE-compliant case-control study.
Marçal, Felipe Franco; Ribeiro, Erlane Marques; Costa, Fábio Wildson Gurgel; Fonteles, Cristiane Sá Roriz; Teles, Gabriela Silva; de Barros Silva, Paulo Goberlânio; Chaves Junior, Cauby Maia; Ribeiro, Thyciana Rodrigues.
Afiliação
  • Marçal FF; Postgraduate Program in Dentistry, Department of Clinical Dentistry, Federal University of Ceará, Fortaleza, Brazil; Professor, School of Dentistry, Christus University Center, Fortaleza, Brazil.
  • Ribeiro EM; Professor, School of Medicine, Christus University Center, Fortaleza, Brazil; Division of Genetics, Children's Hospital Albert Sabin, Fortaleza, Brazil.
  • Costa FWG; Adjunct Professor, Department of Clinical Dentistry, Federal University of Ceará, Fortaleza, Brazil.
  • Fonteles CSR; Full Professor, Department of Clinical Dentistry, Federal University of Ceará, Fortaleza, Brazil.
  • Teles GS; Graduate Student, School of Medicine, Christus University Center, Fortaleza, Brazil.
  • de Barros Silva PG; Postgraduate Program in Dentistry, Department of Clinical Dentistry, Federal University of Ceará, Fortaleza, Brazil; Professor, School of Dentistry, Christus University Center, Fortaleza, Brazil.
  • Chaves Junior CM; Full Professor, Department of Clinical Dentistry, Federal University of Ceará, Fortaleza, Brazil.
  • Ribeiro TR; Adjunct Professor, Department of Clinical Dentistry, Federal University of Ceará, Fortaleza, Brazil. Electronic address: Thyciana_odonto@yahoo.com.br.
Oral Surg Oral Med Oral Pathol Oral Radiol ; 128(6): 621-630, 2019 Dec.
Article em En | MEDLINE | ID: mdl-31399368
OBJECTIVE: This study aimed to assess the prevalence of dental findings on panoramic radiographs (PRs) of patients with osteogenesis imperfecta (OI) and correlate these results with epidemiologic and medical data. STUDY DESIGN: A case-control study was conducted with 24 patients with OI and 48 sex- and age-matched controls. Demographic, clinical, and bisphosphonate regimen-related data were recorded. The outcome variables were the presence or absence of dental alterations in PRs. Mann-Whitney U test, Pearson's χ2 test, and multinomial logistic regression analysis (95% confidence interval) were used (significance level of 5%). RESULTS: OI type 4 demonstrated a high prevalence (62.5%), followed by type 1 (37.5%). With regard to prevalence associated with severity, the moderate form was the most prevalent (P = .028). The mean time of intravenous pamidronate regimen was 6.6 ± 4.4 years. Dentinogenesis imperfecta was observed in 75% of patients with OI, and this group showed a high prevalence of dental abnormalities in comparison with controls (P < .05). Bisphosphonate therapy was associated with ectopic teeth (P = .007) and tooth impaction (P = .033). Pulp obliteration was significant with bisphosphonate treatment over a period of 7 years (P = .026). CONCLUSIONS: This study found a significant prevalence of dental alterations in patients with OI, and certain alterations were associated with bisphosphonate therapy, indicating its influence on the dentin-related physiopathology.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese Imperfeita Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese Imperfeita Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos