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Aneurysmal Subarachnoid Hemorrhage Associated with Small Aneurysms in Smokers and Women: A Retrospective Analysis.
Figueredo, Luisa F; Camila Pedraza-Ciro, María; Sebastian Lopez-McCormick, Juan; Javier Rueda-Esteban, Roberto; Armando Mejía-Cordovez, Juan.
Afiliação
  • Figueredo LF; School of Medicine, Universidad de los Andes, Bogotá, Colombia.
  • Camila Pedraza-Ciro M; School of Medicine, Universidad El Bosque, Bogotá, Colombia.
  • Sebastian Lopez-McCormick J; School of Medicine, Universidad de los Andes, Bogotá, Colombia.
  • Javier Rueda-Esteban R; School of Medicine, Universidad de los Andes, Bogotá, Colombia.
  • Armando Mejía-Cordovez J; Department of General Surgery, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
World Neurosurg X ; 4: 100038, 2019 Oct.
Article em En | MEDLINE | ID: mdl-31360917
BACKGROUND: Previous studies have shown low rupture rates for small aneurysms (<10 mm), suggesting that the risk of treatment could exceed the benefits. However, evidence has changed, showing crescent rates of aneurysmal subarachnoid hemorrhage (aSAH) associated with small aneurysms. We report trends in size, localization, clinical characteristics, and outcomes of intracranial aneurysms (IAs). METHODS: In this retrospective study, a total of 200 clinical histories of patients diagnosed with IAs over an 8-year period were analyzed. Variables considered included age, sex, tobacco consumption, morphological characteristics of the aneurysm, complications, vasospasm, and mortality. Qualitative variables were assessed by measurements of absolute and relative frequency. Smoking behavior, aneurysm size, and aneurysm rupture (AR) were compared using 1-way analysis of variance. Categorical variables were analyzed using Pearson's χ2 test. RESULTS: The average age at presentation was 58 years. The average size of ruptured aneurysms in the general group was 2.5-7.5 mm, and AR was most common in women (76%) and in patients age 50-60 years (33%). The rate of vasospasm was 19%, and mortality was 37%. Smokers composed 32% of the cohort. Heavy smokers had a 57% rate of aSAH, with an average size of rupture of 5 mm. The most common location of aneurysms and AR was the AComA (33%). CONCLUSIONS: Our results suggest increasing AR rates in aneurysms smaller than 10 mm. This trend is seen especially in individuals with heavy tobacco consumption and in women of perimenopausal age. Our findings show a tendency of AR in accordance with previous results and are expected to serve as basis for further research on aneurysm management.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Qualitative_research / Risk_factors_studies Idioma: En Revista: World Neurosurg X Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Qualitative_research / Risk_factors_studies Idioma: En Revista: World Neurosurg X Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Estados Unidos