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Biogenic synthesis of silver nanoparticles using Brazilian propolis.
Barbosa, Valcilaine T; Souza, Joyelanne K C; Alvino, Valter; Meneghetti, Mario R; Florez-Rodriguez, Pedro P; Moreira, Rui E; Paulino, Gustavo V B; Landell, Melissa F; Basílio-Júnior, Irinaldo D; do Nascimento, Ticiano G; Grillo, Luciano A M; Dornelas, Camila B.
Afiliação
  • Barbosa VT; Federal University of Alagoas, Institute of Pharmaceutical Sciences, Maceió, Alagoas, Brazil.
  • Souza JKC; Federal University of Alagoas, Institute of Pharmaceutical Sciences, Maceió, Alagoas, Brazil.
  • Alvino V; Federal University of Alagoas, Institute of Pharmaceutical Sciences, Maceió, Alagoas, Brazil.
  • Meneghetti MR; Federal University of Alagoas, Institute of Chemistry and Biotechnology, Maceió, Alagoas, Brazil.
  • Florez-Rodriguez PP; Federal University of Alagoas, Institute of Chemistry and Biotechnology, Maceió, Alagoas, Brazil.
  • Moreira RE; Tescan of Brazil Scientific Instruments Ltda, São Bernardo do Campo, São Paulo, Brazil.
  • Paulino GVB; Federal University of Alagoas, Institute of Biological Sciences and Health, Maceió, Alagoas, Brazil.
  • Landell MF; Federal University of Alagoas, Institute of Biological Sciences and Health, Maceió, Alagoas, Brazil.
  • Basílio-Júnior ID; Federal University of Alagoas, Institute of Pharmaceutical Sciences, Maceió, Alagoas, Brazil.
  • do Nascimento TG; Federal University of Alagoas, Institute of Pharmaceutical Sciences, Maceió, Alagoas, Brazil.
  • Grillo LAM; Federal University of Alagoas, Institute of Pharmaceutical Sciences, Maceió, Alagoas, Brazil.
  • Dornelas CB; Federal University of Alagoas, Institute of Pharmaceutical Sciences, Maceió, Alagoas, Brazil.
Biotechnol Prog ; 35(6): e2888, 2019 11.
Article em En | MEDLINE | ID: mdl-31353844
Biological methods have been used to synthesize silver nanoparticles through materials such as bacteria, fungi, plants, and propolis due to their reducing properties, stabilizer role and environmentally friendly characteristic. Considering the antimicrobial activity of propolis as well as the broad-spectrum antibacterial effects of silver nanoparticles, this study aim to describe the use of Brazilian propolis to synthesize silver nanoparticles (AgNP-P) and investigate its antimicrobial activity. The synthesis was optimized by factorial design, choosing the best conditions for smaller size particles. AgNP-P demonstrated a maximum absorbance at 412 nm in ultraviolet-visible spectra, which indicated a spherical format and its formation. Dynamic light scattering demonstrated a hydrodynamic size of 109 nm and polydispersity index less than 0.3, showing a good size distribution and stability. After its purification via centrifugation, microscopy analysis corroborates the format and showed the presence of propolis around silver nanoparticle. X-ray diffraction peaks were attributed to the main planes of the metallic silver crystalline structure; meanwhile infrared spectroscopy demonstrated the main groups responsible for silver reduction, represented by ∼22% of AgNP-P indicates by thermal analysis. Our product revealed an important antimicrobial activity indicating a synergism between propolis and silver nanoparticles as expected and promising to be an effective antimicrobial product to be used in infections.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Própole / Nanopartículas Metálicas / Anti-Infecciosos Limite: Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Biotechnol Prog Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Própole / Nanopartículas Metálicas / Anti-Infecciosos Limite: Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Biotechnol Prog Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos