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Imaginological characterization of multiple myeloma lesions of the jaws through cone-beam computed tomography.
Rocha, Thaiza Gonçalves; Feitosa, Édila Figuerêdo; Maiolino, Ângelo; de Magalhães Filho, Roberto José Pessoa; Guedes, Fábio Ribeiro; Torres, Sandra Regina; Visconti, Maria Augusta.
Afiliação
  • Rocha TG; Department of Oral Pathology and Diagnosis, School of Dentistry, Dental Clinic, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Feitosa ÉF; School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Maiolino Â; Medical Clinic, University Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • de Magalhães Filho RJP; University Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Guedes FR; Department of Oral Pathology and Diagnosis, School of Dentistry, Federal University of Rio de Janeiro, Rua Professor Rodolpho Paulo Rocco, 325, Cidade Universitária, Rio de Janeiro, RJ, 21941-617, Brazil.
  • Torres SR; Department of Oral Pathology and Diagnosis, School of Dentistry, Federal University of Rio de Janeiro, Rua Professor Rodolpho Paulo Rocco, 325, Cidade Universitária, Rio de Janeiro, RJ, 21941-617, Brazil.
  • Visconti MA; Department of Oral Pathology and Diagnosis, School of Dentistry, Federal University of Rio de Janeiro, Rua Professor Rodolpho Paulo Rocco, 325, Cidade Universitária, Rio de Janeiro, RJ, 21941-617, Brazil. gutavisconti@odonto.ufrj.br.
Oral Radiol ; 36(2): 168-176, 2020 04.
Article em En | MEDLINE | ID: mdl-31222625
PURPOSE: To establish an evaluation protocol for the identification and description of the variations in multiple myeloma (MM) lesions of the jaws, by means of cone-beam computed tomography (CBCT). MATERIALS AND METHODS: Tomography exams from 33 MM patients were evaluated in this retrospective observational study. The reconstructions were analyzed simultaneously, according to the established protocol, with the following description criteria: anatomic location, size, margins, inner aspect, relationship with adjacent structures, and presence or absence of a punched-out aspect. The exams were further subdivided into groups of patients using, or not bisphosphonates. RESULTS: There were osteolytic lesions in 100% of cases, most of which were extended to more than one anatomical region. Poorly defined margins were more frequent in the maxilla than in the mandible. Extensive bone resorption presenting multilocular areas was the most frequently observed aspect, being 86.2% for maxilla and 87.9% for mandible. In relation to bisphosphonates, patients who used the medication had more poorly defined bone margins and contortions (68.6%) than those who did not undergo drug therapy (31.4%). No well-defined lesions were observed (p = 0.34%). CONCLUSION: It was possible to establish a protocol for evaluation of MM lesions in CBCT images and to identify that when evaluated three-dimensional, lesions tend to be poorly defined and have no pattern of description, as described in two-dimensional "punched-out".
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mieloma Múltiplo Tipo de estudo: Guideline / Observational_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Oral Radiol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Japão

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mieloma Múltiplo Tipo de estudo: Guideline / Observational_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Oral Radiol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Japão